Molecular Research on Osteoarthritis and Osteoporosis

Dear Colleagues,

Osteoarthritis is a degenerative joint disease that affects millions worldwide, leading to chronic pain, impaired mobility, and reduced quality of life. Complementary to this, osteoporosis is a systemic skeletal disorder characterized by reduced bone density, increased risk of fractures, and substantial morbidity. Both diseases pose significant challenges to public health, necessitating a comprehensive understanding of their underlying molecular mechanisms to develop effective prevention strategies, diagnostics, and therapeutic interventions.

This Special Issue aims to provide a comprehensive platform for researchers and scholars to contribute original research articles, reviews, and perspectives addressing the molecular aspects of osteoarthritis and osteoporosis. The objective is to deepen our understanding of the underlying cellular and molecular processes involved in these conditions, ultimately leading to improved diagnostic, prevention, and treatment strategies.

We welcome submissions focusing on various aspects, including, but not limited to, the following:

• The molecular pathways and signaling mechanisms underlying osteoarthritis and osteoporosis development and progression.
• The identification and characterization of biomarkers for early detection, prognosis, and monitoring of these diseases.
• Emerging therapeutic targets and novel molecular interventions to alleviate symptoms and halt disease progression.
• Epigenetic modifications, gene expression regulation, and non-coding RNAs associated with the pathogenesis of osteoarthritis and osteoporosis.
• Advances in genomics, proteomics, and metabolomics studies to unravel the intricate molecular interactions involved in these diseases.
• Animal models, cell culture systems, and innovative molecular tools employed in osteoarthritis and osteoporosis research.

We encourage researchers from diverse disciplines, including molecular biology, biochemistry, genetics, and pharmaceutics, to contribute and collaborate in advancing our knowledge in this field. We also invite clinicians to present their perspectives on translating molecular research findings into clinical applications for the benefit of patients.

Dr. Bo Qiu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• osteoarthritis
• osteoporosis
• signaling pathway
• therapeutic target
• genomics
• metabolomics
• animal model
• epigenetic modifications