The Role of Chemerin in Human Disease—2nd Edition

Dear Colleagues,

This Special Issue, entitled “The Role of Chemerin in Human Disease”, will focus on the selection of recent research topics and up-to-date review articles focusing on the role of chemerin in disease.

Chemerin is a well-characterized adipokine which has multiple functions. Adipose tissue and serum levels are increased in the obese, and chemerin plays a significant role in adipogenesis and glucose homeostasis. The C-terminal processing of chemerin generates biologically active isoforms and, moreover, contributes to chemerin inactivation. Different chemerin isoforms have been identified, but their particular physiological functions remain mostly unknown. Chemerin isoform tissue distribution, signalling pathways, and biological activities require further investigation.

There is emerging evidence that chemerin is an important molecule in various cancers. Leukocyte recruitment via this chemoattractant mostly leads to the suppression of tumor growth, while chemerin-induced angiogenesis is one of its tumor-promoting activities. Chemerin has already been described as a major factor in various diseases, such as coronary artery disease, hypertension, Alzheimer´s disease, and chronic obstructive pulmonary disease.

With this Special Issue of Biomedicines, we aim to collect articles which clarify the pathophysiological role of chemerin in human diseases. Articles investigating chemerin’s role as a biomarker in human diseases are also welcome. Moreover, we invite authors to write review articles providing a comprehensive and critical overview of the current literature.

Prof. Dr. Christa Buechler
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• biomarker
• chemotaxis
• cardiovascular diseases
• cancer
• chemerin isoforms
• CMKLR1
• GPR1
• CCRL2

• The Role of Chemerin in Human Disease in Biomedicines (9 articles)