Eosinophils in Allergy and Related Diseases—Selected Papers from “The Workshop on Eosinophils in Allergy and Related Diseases 2022 and 2023”

Dear Colleagues,

The focus of this Special Issue is the biology or roles of eosinophils in allergy and related diseases, such as asthma, atopic dermatitis, allergic rhinitis, eosinophilic gastrointestinal diseases (EGIDs), hypereosinophilic syndrome (HES), eosinophilic granulomatosis with polyangiitis (EGPA), and eosinophilic chronic rhinosinusitis (ECRS).

Eosinophils play a critical role in the pathogenesis of type two inflammation through the expression of surface receptors, including cytokine and chemokine receptors, lipid mediator receptors, pattern recognition receptors, adhesion molecules, Fc receptors, and Toll-like receptors, while eosinophils have biological functions, including the maintenance of homeostasis, host defense against infections, immune regulation, and anti-inflammatory and antitumorigenic activities. In addition, eosinophil biology itself has still not been fully elucidated.

To understand the biological aspects of eosinophils and associated disease, our workshop, “Workshop on Eosinophils in Allergy and Related Diseases (WEA)”, has been held annually in Japan for more than 30 years. In the annual meeting of the WEA, we discuss subjects regarding eosinophils in allergy, including 1) cell production/differentiation, 2) migration/infiltration, 3) structure/surface receptors, 4) activation, 5) intracellular signal transduction, 6) mediator/cytokine production, 7) role in disease pathogenesis, and 8) case reports.

Here, we selected authors from “The Workshop on Eosinophils in Allergy and Related Diseases 2022 (WEA 2022)” and all WEAs held before to submit papers to this Special Issue of Biomolecules. The purpose of this Special Issue is to contribute to the development of research by promoting a better understanding of the biology and clinical implications of eosinophils.

Prof. Dr. Yoshiyuki Yamada
Prof. Dr. Akira Kanda
Guest Editors

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