Pharmacological Approach to Sepsis and Septic Shock
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: closed (28 February 2021) | Viewed by 4263
Special Issue Editor
Special Issue Information
Dear Colleagues,
Sepsis is a major cause of health loss and mortality worldwide. This systemic illness is caused by a dysregulated host response to infection, which leads to progressive multiple organ dysfunction. Despite its high health-related burden, the pathophysiology of sepsis and multiple organ dysfunction is poorly understood. Early investigations focused on the mechanism of septic shock by looking into the molecular mechanisms involved in impaired vascular reactivity, endothelial function and coagulation. However, none of these ideas has resulted in the development of new treatments. The host response to infection is complex and engages different aspects of physiological control. Recent studies suggest that an interdisciplinary approach may pave the way for future advances in sepsis research. For example, there is evidence that neural stimulation may play a role in the modulation of the host response in sepsis. This suggests an exciting avenue for collaboration among physiologists, neuroscientists, biomedical engineers, immunologists, biophysicists, biochemists and pharmacologists to study this complex life-threatening illness.
This Special Issue intends to present original research articles and up-to-date reviews about the molecular aspects which lead to a better understating of the network of interactions in sepsis, septic shock and multiple organ dysfunction. We look forward to reading your contributions.
Dr. Alireza Mani
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- Sepsis
- septic shock
- septicemia
- multiple organ dysfunction syndrome
- multiorgan failure
