Advanced SERS Biosensors for Detection and Analysis

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Optical and Photonic Biosensors".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 1435

Special Issue Editors


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Guest Editor
School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China
Interests: biosensors; SERS paper chip sensor; 3D nanomaterials; application in environmental analysis

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Guest Editor
School of Chemistry & Materials Science, Jiangsu Normal University, Xuzhou 221116, China
Interests: SERS-based sensing materials and detection methods; spectral analysis techniques for biological molecules in living cells

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Guest Editor
School of Pharmacy and Pharmaceutical Science, Xiamen Medical College, Xiamen 361023, China
Interests: biosensors; surface-enhanced Raman spectroscopy; in situ/operando Raman spectroscopy characterization; rapid Raman detection in the fields of public security and life or health

Special Issue Information

Dear Colleagues,

In recent years, the fields of health diagnosis, food and environmental monitoring, and emergency security have been the focus of extensive scientific research. With environmental pollution, the pressure of work and the pace of life, and unhealthy living habits, the incidence of cardiovascular diseases, cancer, chronic respiratory diseases, diabetes, and mental depression is proliferating year by year. As a crucial component of the human body, biomolecules are widely involved in various physiological activities of the human body and are related to a variety of diseases. Because the trace detection and analysis of biomolecules is closely related to the timely diagnosis of major diseases, food safety and environmental problems, it can be used as a reference for judgment. Therefore, the research of rapid, simple, economical, portable, and location-free sensing platforms is of great practical significance. Surface-enhanced Raman spectroscopy (SERS) detection technology has been widely employed in biological imaging, analytical chemistry, disease diagnosis, food safety and other fields due to its ultra-high sensitivity, rapid spectral acquisition speed, real-time and on-site detection. Accordingly, this Special Issue is dedicated to collecting articles addressing significant advances in innovative research on advanced SERS biosensors for detection and analysis.

Dr. Peini Zhao
Prof. Dr. Lulu Qu
Dr. Min Su
Guest Editors

Manuscript Submission Information

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Keywords

  • SERS
  • biosensor
  • rapid Raman detection
  • SERS-based sensing materials
  • point-of-care testing
  • biochemical analysis

Published Papers (1 paper)

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Research

14 pages, 2952 KiB  
Article
Highly Sensitive and Wide-Range Detection of Thiabendazole via Surface-Enhanced Raman Scattering Using Bimetallic Nanoparticle-Functionalized Nanopillars
by Hyunjun Park, Gayoung Kim, Woochang Kim, Eugene Park, Joohyung Park and Jinsung Park
Biosensors 2024, 14(3), 133; https://doi.org/10.3390/bios14030133 - 4 Mar 2024
Viewed by 1170
Abstract
Thiabendazole (TBZ) is a benzimidazole; owing to its potent antimicrobial properties, TBZ is extensively employed in agriculture as a fungicide and pesticide. However, TBZ poses environmental risks, and excessive exposure to TBZ through various leakage pathways can cause adverse effects in humans. Therefore, [...] Read more.
Thiabendazole (TBZ) is a benzimidazole; owing to its potent antimicrobial properties, TBZ is extensively employed in agriculture as a fungicide and pesticide. However, TBZ poses environmental risks, and excessive exposure to TBZ through various leakage pathways can cause adverse effects in humans. Therefore, a method must be developed for early and sensitive detection of TBZ over a range of concentrations, considering both human and environmental perspectives. In this study, we used silver nanopillar structures (SNPis) and Au@Ag bimetallic nanoparticles (BNPs) to fabricate a BNP@SNPi substrate. This substrate exhibited a broad reaction surface with significantly enhanced surface-enhanced Raman scattering hotspots, demonstrating excellent Raman performance, along with high reproducibility, sensitivity, and selectivity for TBZ detection. Ultimately, the BNP@SNPi substrate successfully detected TBZ across a wide concentration range in samples of tap water, drinking water, juice, and human serum, with respective limits of detection of 146.5, 245.5, 195.6, and 219.4 pM. This study highlights BNP@SNPi as a promising sensor platform for TBZ detection in diverse environments and contributes to environmental monitoring and bioanalytical studies. Full article
(This article belongs to the Special Issue Advanced SERS Biosensors for Detection and Analysis)
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