Special Issue "Implantable Biosensors for in vivo Detection and Measurement"
A special issue of Biosensors (ISSN 2079-6374).
Deadline for manuscript submissions: 15 April 2018
Prof. Dr. Michael Thompson
Implantable sensors that are capable of operation in vivo for the measurement of a variety of biochemical species are becoming of significant interest in a number of fields, ranging from fundamental studies in biology to precision medicine and clinical theranostics. The main requirement is for micro-based devices that can accurately and selectively detect the concentration of biochemical moieties in small volumes of biological fluid for closed-loop modulation. Other important operational criteria are the need for time dependant measurement, avoidance of interference from proteins and other biological fluid containing entities, and possibilities for multiplexed measurement of a number of analytes. The development of such devices clearly presents major challenges among which the amelioration of sensor fouling and requirement for “self-calibration” are paramount. The long-standing effort to develop a glucose sensor for function in tandem with an artificial pancreas configuration represents the classical case regarding these challenges. It is evident that solutions to the various issues mentioned above will require research efforts from a disparate range of disciplines including biology, medicine, electrical and biomedical engineering, clinical biochemistry and surface physical chemistry conducted in a highly interactive fashion. The specific goal of this Special Issue of Biosensors is to aggregate both contributions with respect to addressing the various challenges and applications in terms of measurements in blood, cerebrospinal and interstitial fluid and tissue generally.Prof. Dr. Michael Thompson
Dr. Simon C. Cork
Manuscript Submission Information
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