New Therapeutic Strategies of Radioresistant Tumours by Radiosensitization
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 15 January 2025 | Viewed by 1700
Special Issue Editors
Interests: radioresistant cancer cell biology; tumor cell radiosensitization; DNA damage signaling; mitochondria–nucleus communication; radiation-induced bystander effects; radiation response biomarkers; tumor microenvironment
Special Issues, Collections and Topics in MDPI journals
Interests: cancer cell biology; radiotherapy; particle therapy; DNA damage response; signaling transduction; radiation-induced bystander effects; tumor cell radiosensitization; integrated omics; proteomics; radiation response biomarkers; radioresistance; combined treatments; tumor microenvironment; inflammatory
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, cancer therapy has advanced substantially, thus significantly enhancing the quality of life of cancer patients. However, successful tumor therapy remains a major challenge, particularly in tumors that are resistant to chemo or radiation therapy. The main factor in determining the therapeutic effect is the tumor’s response to radiation, which is correlated with intrinsic or acquired radioresistance after treatment. Consequently, future research must continue to advance our comprehension of the fundamental mechanisms of chemo and radiation resistance when it is related to target mutations, the tumor microenvironment and signaling pathways in cancers. This is in order to identify novel biomarkers and to develop new radiosensitizers and combined strategies that are able to overcome the resistance of tumors to therapy. This Special Issue aims to collect current research in the realm of tumor radiosensitizers, the fundamental mechanisms of radioresistance and the identification of novel biomarkers. Potential topics include, but are not limited to, the following:
- Tumor drug radiosensitizers
- Tumor nanoparticle radiosensitizers
- Fundamental mechanisms of resistance
- Novel biomarkers
- Innovative combined treatments
- Chemo- and radiation-resistant tumors
Dr. Diana Savu
Dr. François Chevalier
Guest Editors
Manuscript Submission Information
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Keywords
- chemo-radiation-resistant tumors
- radiosensitizers
- biomarkers
- mechanisms of radioresistance
- tumor drug radiosensitizers
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