Advances in Geriatric Oncology: Exploring Practical Ways to Optimize Treatment in Older Patients with Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: closed (30 March 2022) | Viewed by 68465
Special Issue Editors
Interests: geriatric oncology; lymphoma
Special Issues, Collections and Topics in MDPI journals
Interests: geriatric oncology; oncologic decision making
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer is a disease of aging with patients over 70 accounting for 50% of newly diagnosed malignancies and 70% of all cancer deaths. Despite this epidemiologic context, older patients with cancer continue to be underrepresented in clinical trials which are necessary to establish new standards of cancer care. This is particularly striking for those with functional decline and/or with comorbid conditions who are usually excluded from clinical trials. As a result, robust data on the benefit/risk balance for many treatment strategies in these older patients are lacking, putting them at increased risk for treatment toxicity. Measures of frailty syndrome by geriatric assessment and biological markers are critical to elucidate risks for morbidity, loss of quality of life, functional impairment, and mortality in older patients with cancer. Treating frailty syndrome via geriatric interventions will likely reduce risk for poor cancer outcomes, but this should first be demonstrated and quantified, so research is needed in this area.
This Special Issue will highlight the role of frailty syndrome in geriatric oncology in all its diversity on both clinical and biological aspects that advance our understanding in order to optimize and personalize cancer treatment. Original articles are preferred, but systematic reviews are also welcome.
Prof. Dr. Elena Paillaud
Prof. Dr. Pierre Soubeyran
Dr. Marije E. Hamaker
Guest Editors
Manuscript Submission Information
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Keywords
- cancer
- older
- frailty
- geriatric assessment
- chemo-toxicities
- overall survival
- cachexia
- biomarker
- comorbidities
- quality of life
- functional status
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