Cytoskeletal Dynamics in Cell Growth, Migration and Invasion
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (30 November 2016) | Viewed by 140
Special Issue Editor
Special Issue Information
Dear Colleagues,
The cytoskeleton, a complex network of filaments and tubules, provides the cell shape and mechanical support for cells to carry out many essential cellular functions, such as cell division, adhesion, and migration. Components of the cytoskeleton play a role in receiving extracellular signals, and are also downstream targets of signalling pathways, integrating changes in cell architecture with other cellular responses. Thus, the regulation of cytoskeleton dynamics is essential for maintaining cellular and organismal homeostasis. Dysregulation of cytoskeleton dynamics has been implicated in many diseases, including cancer, thus prompting a push to identify and characterize the components of the cytoskeleton, regulation of cytoskeleton dynamics, and its role in cell growth, migration, and invasion. Recent advances in molecular, cellular, and imaging techniques have provided us with tools to decipher the regulation of cytoskeleton network in cell physiology and pathology. Furthermore, next generation sequencing has provided the tools to identify mutations in cytoskeleton components to widen our understanding of disease pathology and to identify new biomarkers for molecular stratification of diseases.
In this Special Issue, we invite your contributions, original research articles or reviews, on the regulation of cytoskeleton dynamics, its role in cellular physiology and pathobiology. Articles with mechanistic and functional insights are especially welcome.
Assoc. Prof. Thirumaran Thanabalu
Guest Editor
Manuscript Submission Information
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Keywords
- cell signaling
- cytoskeleton
- cell proliferation
- cell protrusion
- cell migration
- cell adhesion
- invasion
- cancer
- metastasis
