Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Studies of Aging and Anti-Aging Strategies in Animals and Humans
edited by Paweł Kordowitzki
submission deadline 20 Dec 2024 | Viewed by 16 | Submission Open
Keywords: aging; anti-aging; humans; animals; epigenetic clocks; DNA methylation; longevity
(This special issue belongs to the Section Cellular Aging)
Molecular Mechanism of Liver Transplantation
edited by Carmen Peralta and Juan Carlos Cutrin
submission deadline 20 Dec 2024 | Viewed by 9 | Submission Open
Keywords: liver transplantation; ischemia-reperfusion injury; signaling pathways; graft dysfunction; sterile inflammation; liver regeneration; fatty grafts; normothermic machine perfusion; defatting strategies
(This special issue belongs to the Section Tissues and Organs)
Glioblastoma: What Do We Know?
edited by
submission deadline 25 Dec 2024 | 3 articles | Viewed by 2279 | Submission Open
Keywords: carcinoma cell; diagnoses; molecular mechanism; cellular mechanism; signaling pathways; biomarkers; therapeutics
(This special issue belongs to the Section Cells of the Nervous System)
Cellular Glycosphingolipids in Human Disease submission deadline 25 Dec 2024 | 1 articles | Viewed by 1659 | Submission Open
Keywords: glycosphingolipid; cancer; sphingolipid; signal transduction; epithelial to mesenchymal; ceramide; microdomain; chemoresistance; glucosylceramide; ganglioside; globoside; lactoside; neolactoside; sulfatide; GSL
(This special issue belongs to the Section Cellular Pathology)
Molecular and Cellular Basis of Sleep Disorders
edited by
submission deadline 25 Dec 2024 | 2 articles | Viewed by 1293 | Submission Open
Keywords: intermittent hypoxia; sleep fragmentation; sleep deprivation; OSA animal model; biomarkers
Mitochondrial Dysfunction in Neurodegeneration: A Translational Perspective
edited by Hemendra Vekaria
submission deadline 25 Dec 2024 | Viewed by 215 | Submission Open
Keywords: mitochondrial dysfunction; traumatic brain injury; secondary damage; bioenergetics
(This special issue belongs to the Section Cells of the Nervous System)
Fibrosis in Chronic Inflammatory Diseases submission deadline 25 Dec 2024 | Viewed by 144 | Submission Open
Keywords: fibrosis; fibroblasts; myofibroblasts; inflammation; molecular pathways; pathogenetic mechanisms; therapeutic targets
Therapeutic Applications of Magnetotactic Bacteria and Magnetosomes: State-of-the-Art and Perspectives
edited by
submission deadline 25 Dec 2024 | Viewed by 27 | Submission Open
Keywords: biomedical applications; biotechnology; magnetite nanocrystals; magnetosomes; magnetotactic bacteria; nanotechnology; nanotargeting
(This special issue belongs to the Section Cellular Biophysics)
Modeling Developmental Processes and Disorders in Zebrafish submission deadline 31 Dec 2024 | 9 articles | Viewed by 19615 | Submission Open
(This special issue belongs to the Section Cellular Biophysics)
Innate Immunity in Health and Disease submission deadline 31 Dec 2024 | 7 articles | Viewed by 13889 | Submission Open
Keywords: innate immunity; homeostasis; disease; inflammation; PAMPs; DAMPs; pattern recognition receptors; phagocytes; innate lymphoid cells; neutrophils
(This special issue belongs to the Section Cellular Immunology)
Potential of CAR-Based Cellular Immunotherapy for Non-oncologic Disorders submission deadline 31 Dec 2024 | 3 articles | Viewed by 9418 | Submission Open
Keywords: adoptive cell transfer; CAR-T cells; cell engineering; CAR products; CAR-T cell therapy; non-oncologic disorders; autoimmune diseases; cardiometabolic diseases; inflammatory organ fibrosis; senescent cell pathologies; infections
(This special issue belongs to the Section Cellular Immunology)
Understanding Aging Mechanisms to Prevent Age-Related Diseases
edited by Pierre Jouanny, Sonia Hammami, and
submission deadline 31 Dec 2024 | 4 articles | Viewed by 8024 | Submission Open
(This special issue belongs to the Section Cellular Aging)
Recent Research on the Role of Mitochondria in Neurodegeneration
edited by
submission deadline 31 Dec 2024 | 3 articles | Viewed by 4521 | Submission Open
Keywords: mitochondrial; neurodegeneration; metabolism; mitophagy; apoptosis
(This special issue belongs to the Section Cells of the Nervous System)
Advances in Zebrafish Cardiac Disease Models
edited by
submission deadline 31 Dec 2024 | 2 articles | Viewed by 3839 | Submission Open
Keywords: zebrafish; heart; cardiomyocytes; heart disease; cardiac hypertrophy; regenerative medicine; cardiac regeneration; translational models
(This special issue belongs to the Section Cells of the Cardiovascular System)
Select Topics in Molecular and Cellular Mechanisms of Mammalian Reproduction
edited by Zhengui Zheng, and Liang Ma
submission deadline 31 Dec 2024 | 3 articles | Viewed by 3644 | Submission Open
Keywords: reproductive organ development; sexual differentiation; reproductive tract function; fertilization; implantation; placentation; parturition; lactation
(This special issue belongs to the Section Reproductive Cells and Development)
Human Dental Pulp Stem Cells: Isolation, Cultivation and Applications
edited by
submission deadline 31 Dec 2024 | 2 articles | Viewed by 2053 | Submission Open
Keywords: dental pulp stem cell; stem cell engineering; mesenchymal stem cell; detin-pulp complex regeneration; dentinogenesis; odontoblastic dental pulp stem cell regeneration; dental pulp stem cell in neural regeneration
(This special issue belongs to the Section Stem Cells)
Cancer Immunotherapy Harnessing Innate and Adaptive Immune Effector Cells and PD-1 Immune Checkpoint Inhibitors
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 2051 | Submission Open
Keywords: PD-1 immune checkpoint; CAR-T cells; γ δ T cells; NK cells
(This special issue belongs to the Section Cellular Immunology)
Redox and Metabolic Profile of Cancer
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1881 | Submission Open
Keywords: cancer; metabolism; redox biology; redox-metabolic reprogramming; reactive species: oxygen; nitrogen; sulfur; etc; cancer microenvironment; cancer-tissue cooperation; mitochondria
(This special issue belongs to the Section Cellular Metabolism)
Exclusive Review Papers in Autophagy—Second Edition
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1469 | Submission Open
Keywords: biquitination; autophagy; peroxisomes; macroautophagy; pexophagy; mitophagy; lysosome; vacuole; organellar homeostasis; posttranslational modifications; lipids; signaling cascades
(This special issue belongs to the Section Autophagy)
Mitochondrial Biology and Pathophysiology
edited by and Laura Formentini
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1395 | Submission Open
Keywords: mitochondria; age-related diseases; animal models; cell death; immune responses; metabolic responses; mitochondrial structure; dynamics and function proteostasis
(This special issue belongs to the Section Cellular Pathology)
mTOR Signaling in Metabolism and Cancer 2.0
edited by and
submission deadline 31 Dec 2024 | 1 articles | Viewed by 1152 | Submission Open
Keywords: mTOR; metabolism; cancer; Akt
(This special issue belongs to the Section Cell Proliferation and Division)
The Double Face of Smooth Muscle Cells in Vascular Biology—Friends or Foes, Damage or Regeneration?
edited by
submission deadline 31 Dec 2024 | 1 articles | Viewed by 981 | Submission Open
Keywords: vascular smooth muscle cells; phenotypic modulation; vascular disease; stem cell differentiation; vascular tissue engineering; regenerative medicine
(This special issue belongs to the Section Cells of the Cardiovascular System)
Molecular Mechanisms Involved in Musculoskeletal and Other Tissue Injuries and Disruptions—Regenerative Potential of Exercise submission deadline 31 Dec 2024 | 1 articles | Viewed by 837 | Submission Open
Keywords: tissue injury; tissue regeneration; growth factors; inflammation; oxidative stress; metabolic stress; myokines; adipokines; neurokines; hypertrophy; biochemical pathways; skeletal muscles; liver/hepatic regeneration; brain/neuroplasticity; adipose tissue; varia
(This special issue belongs to the Section Tissues and Organs)
Signaling Pathways and Mechanisms in Cancer Therapy Resistance submission deadline 31 Dec 2024 | Viewed by 756 | Submission Open
Keywords: cancer therapy; therapy resistance; molecular mechanisms; cell signaling pathways; genetic and epigenetic modifications; combination therapies
Gastrointestinal Disease: From Cellular Mechanisms to Targeted Therapy submission deadline 31 Dec 2024 | Viewed by 264 | Submission Open
Keywords: gastrointestinal cancer; gastric cancer; colorectal cancer; esophageal cancer; liver cancer; pancreatic cancer; inflammatory bowel disease; miRNAs; in vitro and in vivo models; molecular networks; molecular pathways; translational medicine; epithelial barrier functions/processes
Bone Regeneration and Repair: Replacing What Has Been Lost through Science
edited by Paolo Savadori
submission deadline 31 Dec 2024 | Viewed by 194 | Submission Open
Keywords: bone; regenerative; bone defect; tissue engineering; histology; animal models; bone biology; 3D printing; biomaterials; bone surgery
Kynurenic Acid: Unveiling Its Impact on the Brain’s Neurotransmission and Neurological Disorders
edited by Korrapati V. Sathyasaikumar, Sarah Beggiato and
submission deadline 31 Dec 2024 | Viewed by 174 | Submission Open
Keywords: kynurenic acid; cognition; aging; neuromodulation; neurodegeneration; neurodevelopment; neuroinflammation; tryptophan catabolism
(This special issue belongs to the Section Cell Signaling)
Graft versus Host Disease (GVHD) after Hematopoietic Cell Transplantation
edited by Senthilnathan Palaniyandi
submission deadline 31 Dec 2024 | Viewed by 158 | Submission Open
Keywords: acute graft versus host disease; chronic graft versus host disease; hematopoietic cell transplantation; transplant immunology
(This special issue belongs to the Section Cellular Immunology)
Head and Neck Squamous Cell Carcinomas: Biomarkers and Cellular Mechanisms towards a Precision Therapy
edited by
submission deadline 31 Dec 2024 | Viewed by 153 | Submission Open
Keywords: head and neck cancer; biomarkers; prognosis; precision therapy; immunotherapy; translational research; immune contexture
(This special issue belongs to the Section Cell Methods)
The Role of IgE and IgG Antibodies in Allergic Reactions: Cellular Mechanisms and Biological Implications
edited by and Paul Engeroff
submission deadline 31 Dec 2024 | Viewed by 146 | Submission Open
Keywords: IgE; IgG; allergy; inflammation; glycosylation; immunotherapy; autoantibodies; Fc receptors; soluble receptors
(This special issue belongs to the Section Cellular Immunology)
Formation, Aggregation, Persistence, and Maturation of NETs
edited by , , and Maximilian Dölling
submission deadline 31 Dec 2024 | Viewed by 143 | Submission Open
Keywords: mechanisms of NET formation; NETs in diseases; degradation of NETs; NET therapeuticals; benefical NETs
(This special issue belongs to the Section Cellular Immunology)
Critical Targets and Therapeutic Strategies of Breast Cancer submission deadline 31 Dec 2024 | Viewed by 138 | Submission Open
Keywords: biomarkers; microenvironment; subtypes; dormancy; therapy; resistance
Updates on the Mechanisms and Therapies of Cardiometabolic Disease submission deadline 31 Dec 2024 | Viewed by 116 | Submission Open
Keywords: cardiovascular disease; atherosclerosis; metabolic disease; hyperlipidemia; diabetes; proatherogenic lipoproteins; drug discovery; gene therapy/gene editing; ASO; mAb
(This special issue belongs to the Section Cells of the Cardiovascular System)
CDKs and CDK-Interacting Proteins/Kinase-Inhibitory Proteins in Human Health and Disease submission deadline 31 Dec 2024 | Viewed by 106 | Submission Open
Keywords: Cell cycle; CDKs; cyclins; CIP/Kip proteins; INK4 family; p53; transcriptional regulation; DNA damage; cytoskeleton; metabolism; senescence; cell death; cell commitment and  differentiation; stem cell; tissue regeneration; embryogenesis; development; growth-related diseases; cancer; sensitivity/resistance to therapy; target therapy
Neuroendocrine Regulation of Metabolic Balance
edited by Chunmei Wang
submission deadline 31 Dec 2024 | Viewed by 102 | Submission Open
Keywords: neuroendocrine system; glucose balance; energy balance
(This special issue belongs to the Section Cells of the Nervous System)
New Molecular and Computational Approaches to Study Immune and Metabolic Interactions in Cancer Biology
edited by Federica Mornata, Luca De Feo, Rebecca Polidori and
submission deadline 31 Dec 2024 | Viewed by 93 | Submission Open
Keywords: solid and liquid cancer; cancer metabolism; tumor microenvironment; digital pathology; immunoncology
(This special issue belongs to the Section Cell Methods)
Identifying Novel Targets and Mechanisms That Drive Pathogenic Fibrosis and Cancer
edited by Gerlinde Wernig and
submission deadline 31 Dec 2024 | Viewed by 82 | Submission Open
Keywords: fibrosis; cancer; extracellular matrix; inflammation; epithelial-to-mesenchymal transition; oxidative stress; cellular senescence; hippo pathway; fibroblast activation
(This special issue belongs to the Section Cellular Pathology)
From Research to Legalization: How Cannabis Exploits the Endocannabinoid System
edited by Erik Keimpema and Tibor Harkany
submission deadline 31 Dec 2024 | Viewed by 73 | Submission Open
Keywords: endocannabinoids; cannabis; legalization; THC; disease; development
Molecular Mechanisms of Neuropathic Pain submission deadline 31 Dec 2024 | Viewed by 37 | Submission Open
Keywords: neuropathic pain; nociplastic pain; fibromyalgia; brain-immune connection; sexual dimorphism; glial cells; lysophosphatidic acid
(This special issue belongs to the Section Cells of the Nervous System)
Advances in Intestinal Epithelial Plasticity and Regeneration
edited by
submission deadline 31 Dec 2024 | Viewed by 36 | Submission Open
Keywords: intestinal epithelium; epithelial plasticity; stem cells; tissue repair; self-renewal; regeneration
Advances in the Study of Neuroinflammation submission deadline 31 Dec 2024 | Viewed by 30 | Submission Open
Keywords: neuroinflammation; neurodegenerative disease; bacterial meningitis; glia cell; microglial cell; macrophage; astrocyte; blood– brain barrier; meninges; meningeal immunity; meningeal lymphatic vessels
(This special issue belongs to the Section Cells of the Nervous System)
Cellular and Molecular Mechanisms in Immune Regulation
edited by Fábio Rinaldo Santori and Natalia B. Ivanova
submission deadline 31 Dec 2024 | Viewed by 28 | Submission Open
Keywords: innate immunity; dendritic cells; macrophages; T cells; B cells; cytokines; immunotherapy
The Potential of Induced Pluripotent Stem Cells
edited by Yun Chang
submission deadline 31 Dec 2024 | Viewed by 24 | Submission Open
Keywords: pluripotent stem cells; reprogramming; engineering; regenerative medicine; differentiation; therapeutic applications; biomaterials
(This special issue belongs to the Section Stem Cells)
The Role of Microglia in Neurodegenerative Diseases and Neuroinflammation
edited by
submission deadline 15 Jan 2025 | Viewed by 34 | Submission Open
Keywords: microglia; central nervous system; neurodegenerative diseases; neurodegeneration; Alzheimer’ s disease (AD); Parkinson’ s disease (PD)
(This special issue belongs to the Section Cellular Aging)
Signaling in Cancer Stem Cells
edited by Upasana Ray
submission deadline 30 Jan 2025 | Viewed by 86 | Submission Open
Keywords: cancer stem cells (CSCs); stem cells signaling pathways; cancer progression and metastasis; therapeutic resistance; targeting cancer stem cells signaling; cancer heterogeneity; targeted therapy for CSCs; identifying biomarkers for CSCs
(This special issue belongs to the Section Stem Cells)
Advanced Technology for Cellular Imaging
edited by Alessandro Grinzato, and
submission deadline 31 Jan 2025 | 2 articles | Viewed by 1861 | Submission Open
Keywords: electron tomography; fluorescence microscopy; live cell imaging; multimodal imaging; super resolution microscopy; cell– cell interaction
(This special issue belongs to the Section Cell Methods)
Molecular and Cellular Mechanisms of Cardiovascular and Metabolic Diseases
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1853 | Submission Open
Keywords: mitochondrial dysfunction; endoplasmic reticulum (ER) stress; oxidative/nitrosative stress; diabetes; obesity; diet; atherosclerosis; hypertension; metabolomics; cell death; nutraceuticals/functional foods
(This special issue belongs to the Section Cells of the Cardiovascular System)
Mitochondria and Other Organelles in Neurodegenerative Diseases
edited by Tian Liu
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1501 | Submission Open
Keywords: mitochondria dysfunction; ER stress; TDP-43 pathology; protein aggregation; tauopathy; neuroinflammation; neurodegeneration; neurodegenerative diseases; therapeutic approaches
(This special issue belongs to the Section Intracellular and Plasma Membranes)
New Targets and Therapeutic Approaches Based on Molecular Mechanisms in Tumorigenesis and Cancer Metastasis
edited by
submission deadline 31 Jan 2025 | Viewed by 60 | Submission Open
Keywords: metastasis; cancer; therapy; precision medicine; cancer stem cells; immuno-oncology; tumor microenvironment; antibody
(This special issue belongs to the Section Cell Microenvironment)
Cellular and Molecular Events in Intervertebral Disc Development, Homeostasis and Disease
edited by
submission deadline 31 Jan 2025 | Viewed by 50 | Submission Open
Keywords: disc development; healthy intervertebral disc; IVD
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