Laboratory Diagnosis of Tuberculosis

Dear Colleagues,

Tuberculosis (TB), caused by the microorganism Mycobacterium tuberculosis (MTB), is the second leading infectious killer globally, following COVID-19. It remains a persistent threat, leading to new infections and re-infections on a worldwide scale. In 2022 alone, an estimated 10.6 million individuals were infected with TB, underscoring the ongoing impact of this disease. Compounding this challenge is the emergence of new strains of multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB, which continue to be identified.

Recent advances in TB diagnosis, including culturing techniques, protein assays, and nucleic acid tests, have significantly elevated the precision of TB detection and treatment. Notably, innovations in point-of-care and decentralized TB tests have broadened the scope of TB diagnosis to reach new patients and access critical resource-challenged environments. In this Special Issue on TB, we invite the submission of manuscripts focusing on MTB detection and laboratory enhancements in TB diagnosis. This encompasses a wide range of topics, including, but not limited to, laboratory-based and point-of-care TB diagnostics, along with methodologies for identifying drug susceptibility markers from clinical samples. Accepted submission types encompass research articles, short research notes, and reviews. Your contributions are invaluable in advancing our understanding of TB.

Dr. Luke T. Daum
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• MTB
• tuberculosis
• qPCR
• NGS
• sample collection
• nucleic acid testing
• rapid antigen testing
• biosensors
• MDR
• XDR
• drug susceptibility testing
• culture analysis