Journal Description
Healthcare
Healthcare
is an international, scientific, peer-reviewed, open access journal on health care systems, industry, technology, policy, and regulation, and is published semimonthly online by MDPI. Ocular Wellness & Nutrition Society (OWNS) is affiliated with Healthcare and its members receive discounts on article processing charges.
- Open Access— free for readers, with article processing charges (APC) paid by authors or their institutions.
- High Visibility: indexed within Scopus, SCIE and SSCI (Web of Science), PubMed, PMC, and other databases.
- Journal Rank: JCR - Q2 (Health Care Sciences and Services) / CiteScore - Q2 (Leadership and Management)
- Rapid Publication: manuscripts are peer-reviewed and a first decision is provided to authors approximately 20.5 days after submission; acceptance to publication is undertaken in 2.7 days (median values for papers published in this journal in the first half of 2024).
- Recognition of Reviewers: reviewers who provide timely, thorough peer-review reports receive vouchers entitling them to a discount on the APC of their next publication in any MDPI journal, in appreciation of the work done.
- Companion journals for Healthcare include: Trauma Care and European Burn Journal.
Impact Factor:
2.4 (2023);
5-Year Impact Factor:
2.5 (2023)
Latest Articles
Regional Variations in Physical Fitness in Children and Adolescents in Shaanxi Province
Healthcare 2024, 12(18), 1890; https://doi.org/10.3390/healthcare12181890 (registering DOI) - 20 Sep 2024
Abstract
Objectives: This study aims to examine the geographical variation in physical fitness levels among Chinese children and adolescents in Shaanxi province. Methods: A total of 19,175 children from Shaanxi province with physical fitness data in 2019, participated in the study. Physical fitness was
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Objectives: This study aims to examine the geographical variation in physical fitness levels among Chinese children and adolescents in Shaanxi province. Methods: A total of 19,175 children from Shaanxi province with physical fitness data in 2019, participated in the study. Physical fitness was assessed using body mass index, force vital capacity, 50 m sprint, sit and reach, 1 min rope skipping, sit-ups, 50 m × 8 round-trip running, standing long jump, pull-ups, 800 m, and 1000 m running, and their standardized scores were aggregated to form a summary score. The total score is used to classify the physical fitness levels into four grades (excellence to failure). Results: The Guanzhong (GZ) region scored the highest, while Northern Shaanxi (NS) scored the lowest. The excellence rate for physical fitness was highest in GZ and lowest in NS, while the failure rate was highest in NS and lowest in GZ. Notably, children and adolescents in NS demonstrated the best endurance levels despite their overall lower fitness scores. The comprehensive physical fitness among Chinese children and adolescents in Shaanxi province showed significant regional disparities. GZ region exhibited the highest physical fitness levels, while Northern Shaanxi had the lowest. Conclusions: Region-specific interventions and targeted health policies are essential to address these disparities and improve the overall physical health status of children and adolescents in Shaanxi province.
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Open AccessArticle
The Impact of Starting Positions and Breathing Rhythms on Cardiopulmonary Stress and Post-Exercise Oxygen Consumption after High-Intensity Metabolic Training: A Randomized Crossover Prospective Study
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Yuanyuan Li, Jiarong Wang, Yuanning Li, Dandan Li, Yining Xu and Yi Li
Healthcare 2024, 12(18), 1889; https://doi.org/10.3390/healthcare12181889 (registering DOI) - 20 Sep 2024
Abstract
Background: The exploration of optimizing cardiopulmonary function and athletic performance through high-intensity metabolic exercises (HIMEs) is paramount in sports science. Despite the acknowledged efficacy of HIMEs in enhancing cardiopulmonary endurance, the high metabolic stress imposed on the cardiopulmonary system, especially for amateurs, necessitates
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Background: The exploration of optimizing cardiopulmonary function and athletic performance through high-intensity metabolic exercises (HIMEs) is paramount in sports science. Despite the acknowledged efficacy of HIMEs in enhancing cardiopulmonary endurance, the high metabolic stress imposed on the cardiopulmonary system, especially for amateurs, necessitates a scaled approach to training. Objective: The aim of this study is to ascertain whether adjustments in the initiation posture and the adoption of an appropriate breathing strategy can effectively mitigate the cardiopulmonary stress induced by HIMEs without compromising training efficacy. Methods: Twenty-two subjects were recruited into this study. The post-exercise heart rate (PHR) and post-exercise oxygen consumption rate (POCR) were collected within 30 min after exercise. A two-way ANOVA, multi-variable Cox regression, and random survival forest machine learning algorithm were used to conduct the statistical analysis. Results: Under free breathing, only the maximum POCR differed significantly between standing and prone positions, with prone positions showing higher stress (mean difference = 3.15, p < 0.001). In contrast, the regulated breathing rhythm enhanced performance outcomes compared to free breathing regardless of the starting position. Specifically, exercises initiated from prone positions under regulated breathing recorded a significantly higher maximum and average PHR than those from standing positions (maximum PHR: mean difference = 13.40, p < 0.001; average PHR: mean difference = 6.45, p < 0.001). The multi-variable Cox regression highlighted the starting position as a critical factor influencing the PHR and breathing rhythm as a significant factor for the POCR, with respective variable importances confirmed by the random survival forest analysis. These results underscore the importance of controlled breathing and starting positions in optimizing HIME outcomes. Conclusions: Regulated breathing in high-intensity exercises enhances performance and physiological functions, emphasizing the importance of breathing rhythm over starting position. Effective training should balance exercise volume and technique to optimize performance and minimize stress, reducing overtraining and injury risks.
Full article
(This article belongs to the Special Issue Physical Fitness—Effects on Muscle Function and Sports Performance)
Open AccessArticle
Assessing Misophonia in Young Adults: The Prevalence and Psychometric Validation of the MisoQuest Questionnaire
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Lourival de Almeida Silva, Matias Noll, Gabriel Cunha Siqueira and Alana Karolyne N. Barbosa
Healthcare 2024, 12(18), 1888; https://doi.org/10.3390/healthcare12181888 (registering DOI) - 20 Sep 2024
Abstract
Background/Objectives: Misophonia, characterized by strong emotional reactions to specific sounds, poses significant challenges, particularly in academic settings. This study aimed to examine the psychometric properties of the Brazilian version of the MisoQuest in a sample of high school and university students. The primary
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Background/Objectives: Misophonia, characterized by strong emotional reactions to specific sounds, poses significant challenges, particularly in academic settings. This study aimed to examine the psychometric properties of the Brazilian version of the MisoQuest in a sample of high school and university students. The primary objective was to assess its reliability and structural validity to enhance understanding of misophonia in young adults. Methods: A total of 549 students (Mean age = 23.2 years, SD = 9.3; 285 females, 260 males, 4 individuals who did not disclose their gender) participated. Both exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were employed to evaluate the MisoQuest. Fit indices for unifactorial and trifactorial models were compared. Internal consistency was assessed using Cronbach’s alpha. Results: The EFA suggested a dominant single-factor structure with high factor loadings (ranging from 0.60 to 0.79). However, the CFA revealed excellent fit for both unifactorial (CFI and TLI = 1.00, RMSEA close to zero) and trifactorial models (CFI and TLI = 1.00, RMSEA = 0.037). The MisoQuest demonstrated high internal consistency (Cronbach’s alpha = 0.93). Additionally, 4.5% of participants were identified as positive for misophonia based on a predefined cutoff score of 61. Conclusions: The Brazilian version of the MisoQuest is a reliable and valid tool for assessing misophonia. These findings suggest that the instrument may capture multiple dimensions of the disorder. Given the observed prevalence of misophonia and its impact on students, early identification and tailored interventions are crucial for providing adequate support. Further research is needed to refine the tool and expand its clinical utility.
Full article
Open AccessArticle
Effects of 12 Weeks of Combined Exercise Training in Normobaric Hypoxia on Arterial Stiffness, Inflammatory Biomarkers, and Red Blood Cell Hemorheological Function in Obese Older Women
by
Wonil Park, Hun-Young Park and Sung-Woo Kim
Healthcare 2024, 12(18), 1887; https://doi.org/10.3390/healthcare12181887 (registering DOI) - 20 Sep 2024
Abstract
Background/Objectives: The present study examined the effect of 12-week combined exercise training in normobaric hypoxia on arterial stiffness, inflammatory biomarkers, and red blood cell (RBC) hemorheological function in 24 obese older women (mean age: 67.96 ± 0.96 years). Methods: Subjects were randomly divided
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Background/Objectives: The present study examined the effect of 12-week combined exercise training in normobaric hypoxia on arterial stiffness, inflammatory biomarkers, and red blood cell (RBC) hemorheological function in 24 obese older women (mean age: 67.96 ± 0.96 years). Methods: Subjects were randomly divided into two groups (normoxia (NMX; n = 12) and hypoxia (HPX; n = 12)). Both groups performed aerobic and resistance exercise training programs three times per week for 12 weeks, and the HPX group performed exercise programs in hypoxic environment chambers during the intervention period. Body composition was estimated using bioelectrical impedance analysis equipment. Arterial stiffness was measured using an automatic waveform analyzer. Biomarkers of inflammation and oxygen transport (tumor necrosis factor alpha, interleukin 6 (IL-6), erythropoietin (EPO), and vascular endothelial growth factor (VEGF)), and RBC hemorheological parameters (RBC deformability and aggregation) were analyzed. Results: All variables showed significantly more beneficial changes in the HPX group than in the NMX group during the intervention. The combined exercise training in normobaric hypoxia significantly reduced blood pressure (systolic blood pressure: p < 0.001, diastolic blood pressure: p < 0.001, mean arterial pressure: p < 0.001, pulse pressure: p < 0.05) and brachial–ankle pulse wave velocity (p < 0.001). IL-6 was significantly lower in the HPX group than in the NMX group post-test (p < 0.001). Also, EPO (p < 0.01) and VEGF (p < 0.01) were significantly higher in the HPX group than in the NMX group post-test. Both groups showed significantly improved RBC deformability (RBC EI_3Pa) (p < 0.001) and aggregation (RBC AI_3Pa) (p < 0.001). Conclusions: The present study suggests that combined exercise training in normobaric hypoxia can improve inflammatory biomarkers and RBC hemorheological parameters in obese older women and may help prevent cardiovascular diseases.
Full article
(This article belongs to the Special Issue Non-pharmacological Interventions in Older Adults)
Open AccessArticle
Dentitions of Long-Term Care Residents: Tooth Types, Roles in Occlusion and Association with Dementia
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Jesse Tervonen, Lina Julkunen, Riitta K.T. Saarela, Kaija Hiltunen and Päivi Mäntylä
Healthcare 2024, 12(18), 1886; https://doi.org/10.3390/healthcare12181886 (registering DOI) - 20 Sep 2024
Abstract
Background/Objectives: Many older adults living in long-term care (LTC) environments have varying numbers of retained natural teeth. The objective of this study was to assess the disease findings based on tooth type and estimate the role of tooth types in occlusion. Methods: We
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Background/Objectives: Many older adults living in long-term care (LTC) environments have varying numbers of retained natural teeth. The objective of this study was to assess the disease findings based on tooth type and estimate the role of tooth types in occlusion. Methods: We conducted clinical oral examinations of 276 LTC residents. The disease findings were analyzed for each tooth type and to determine their associations with dementia. Results: In total, 67.8% of the participants had molar teeth. Premolars/canines were often present as residual roots and had caries. Deepened periodontal pockets and higher plaque index (PI) values for molars had odds ratios of 2.5 (95% confidence interval [CI] of 1.59–3.91) and 1.61 (95% CI of 1.29–2.02), respectively. Participants with dementia were more likely to have incisors and premolars/canines in the form of root remnants and higher PI scores for all tooth types (p ≤ 0.01), as well as more deepened periodontal pockets in all teeth (p = 0.029), than those without dementia. The median number of remaining molars per participant was 3 out of a maximum of 12 (95% CI 3.4–4.0); thus, they often lacked occlusal contact. Conclusions: The LTC residents’ molars were more prone to periodontal problems, whereas their premolars/canines often had caries or were present in the form of root remnants, especially in the participants with dementia. People’s teeth should be treated in an easy-to-maintain way before they move into LTC to enable daily oral hygiene measures and maintain oral health.
Full article
(This article belongs to the Special Issue Oral Health and Quality of Life in Older People)
Open AccessArticle
Stress among Nursing Students in the Era of the COVID-19 Pandemic
by
Grzegorz Kobelski, Katarzyna Naylor, Aleksandra Kobelska and Mariusz Wysokiński
Healthcare 2024, 12(18), 1885; https://doi.org/10.3390/healthcare12181885 (registering DOI) - 20 Sep 2024
Abstract
Introduction: The COVID-19 pandemic has significantly impacted stress levels across various professions, particularly in the medical field. This increase in stress has also affected medical students, including nursing students, who faced unprecedented and challenging circumstances. Nursing students, in particular, experienced added pressure due
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Introduction: The COVID-19 pandemic has significantly impacted stress levels across various professions, particularly in the medical field. This increase in stress has also affected medical students, including nursing students, who faced unprecedented and challenging circumstances. Nursing students, in particular, experienced added pressure due to observing the frontline experiences of nurses and the new demands placed upon them. Aim: This study aimed to assess whether the COVID-19 pandemic affected an increase in stress levels among nursing students in Poland during the pandemic. We also attempt to determine whether there is a correlation between the stress level of students and factors such as gender, age, place of residence, marital status, and level of education. Assuming that the stress level will be higher among women of increasing age and bachelor’s students, we also assumed, however, that lower stress levels would occur among people in relationships and living in the countryside. Materials and Methods: The study was conducted from 27 April 2022 to 12 May 2022. We chose that period as it was the final one of the COVID-19 pandemic, and there was an increasing amount of discussion concerning its cessation, with the public accustomed to its presence in our everyday lives. Since we wanted to determine the stress level experienced by students, we decided to use the standardized Perceived Stress Scale (PSS-10). We enriched the study with sociodemographic questions to investigate the potential impact of these characteristics on the degree of stress experienced. Results: The average score obtained by respondents on the PSS-10 was 19.57 ± 6.03. Of the respondents, 49% reported experiencing a high level of stress. No statistically significant differences were found between the mean PSS-10 scores and the gender (Z = 0.169; p = 0.865), age (F = 1.282, p = 0.281), marital status (Z = −0.776, p = 0.437), or place of residence (urban vs. rural) (Z = −0.784, p = 0.433) of the respondents. The mean PSS-10 scores were also analyzed regarding the level of education (bachelor’s vs. master’s). Bachelor’s students had an average PSS-10 score of 18.95 ± 6.42, while master’s students scored 20.05 ± 5.70. Again, no statistically significant differences were found (t = −1.102, p = 0.2720). Conclusions: The study indicated that nursing students experience high stress levels regardless of gender, age, marital status, place of residence, or level of education. High stress levels were reported among both bachelor’s and master’s students.
Full article
(This article belongs to the Special Issue Human Health before, during, and after COVID-19)
Open AccessArticle
Correlation of Near-Infrared Spectroscopy (NIRS) with Invasive Arterial Pressure Monitoring during Aortic Coarctation Surgery in Pediatric Patients
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Jelena Pjevalica Dragic, Tatjana Zecevic, Ivan Divac, Andrija Pavlovic, Dejan Bisenic, Luka Stanisic, Jasna Kalanj, Igor Stefanovic, Dejan Nikolic, Ivana Petrov and Vladimir Milovanovic
Healthcare 2024, 12(18), 1884; https://doi.org/10.3390/healthcare12181884 (registering DOI) - 20 Sep 2024
Abstract
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Aortic coarctation surgery in pediatric patients requires the placement of two arterial cannulas to monitor pressure gradients and surgical correction adequacy. Near-infrared spectroscopy (NIRS) monitoring provides insight into regional blood flow. This study aimed to investigate the correlation between NIRS values and invasive
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Aortic coarctation surgery in pediatric patients requires the placement of two arterial cannulas to monitor pressure gradients and surgical correction adequacy. Near-infrared spectroscopy (NIRS) monitoring provides insight into regional blood flow. This study aimed to investigate the correlation between NIRS values and invasive arterial pressures, exploring NIRS monitoring as a potential substitute for arterial cannulation. In a cohort of 21 consecutive pediatric patients undergoing aortic coarctation surgery, recordings of NIRS and invasive arterial pressure values were evaluated at various time intervals. Pearson correlation evaluated the relationship between NIRS values and invasively measured arterial pressures. Moderate to strong correlations were observed between the mean arterial pressure (MAP) of the upper and lower arteries and cerebral (rSO2-C) and somatic (rSO2-S) NIRS values 5 min after cross-clamp placement (r = 0.621, p = 0.003; r = 0.757, p < 0.001). Strong correlations were found 15 min after cross-clamp placement (r = 0.828, p = 0.002; r = 0.783, p = 0.004). Before transfer to the ICU, a strong correlation existed between the upper artery MAP and rSO2-C (r = 0.730, p < 0.001), but there was no correlation between the lower artery MAP and rSO2-S. These findings are promising, but further studies are required to validate it as a reliable substitute for invasive pressure monitoring in this patient population.
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Open AccessProtocol
Factors Influencing the Participation of Shared Decision Making in Stable Coronary Artery Disease Patient: Protocol of a Mixed Methods Study
by
Xiangxu Meng, Chengang Hong and Xingwei Zhang
Healthcare 2024, 12(18), 1883; https://doi.org/10.3390/healthcare12181883 - 20 Sep 2024
Abstract
Introduction: The “paternalistic decision-making model” is no longer well suited to the modern clinical environment, and therefore, shared decision making (SDM) has emerged as a key approach. Although the benefits of SDM have been largely reported, several studies have reported low participation in
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Introduction: The “paternalistic decision-making model” is no longer well suited to the modern clinical environment, and therefore, shared decision making (SDM) has emerged as a key approach. Although the benefits of SDM have been largely reported, several studies have reported low participation in SDM in coronary artery disease (CAD) patients. The theory of planned behavior (TPB) model is one of the most frequently employed theoretical frameworks for predicting human behaviors. According to the TPB, intention is influenced by attitude, subjective norm, and perceived behavioral control, while behavior is influenced by both intention and perceived behavioral control. Therefore, we propose a mixed methods study based on TPB to investigate the status of Chinese stable coronary artery disease (SCAD) patients’ participation in SDM, understand their experiences of SDM, and explore the factors that influence their participation in SDM. Materials and Methods: An explanatory sequential mixed methods design will be used to explore the study aims, including a quantitative phase, a subsequent qualitative phase, and the final integration study. The quantitative study will use convenient sampling from the Affiliated Hospital of Hangzhou Normal University to conduct a cross-sectional survey (n ≥ 252). The qualitative study will be sampled using the maximum difference sampling method from the quantitative study results, and then the data will be collected through semi-structured interviews (n = 10–20). This study will use descriptive statistics and test hypotheses while considering a p-value of <0.05, which will be considered statistically significant. Discussions: The study employs a mixed method approach with an explanatory sequential design, incorporating qualitative and quantitative methods to comprehensively understand the factors influencing SCAD patients’ participation in SDM. Furthermore, these findings can inform the design of future intervention studies and provide healthcare providers with targeted information and communication to help SCAD patients make the most appropriate decisions. Study participants will be recruited using convenience sampling from just one single clinical setting, which may limit the findings’ generalizability. Ethics and Dissemination: This study has been approved by the Ethical Committee of the School of Nursing, Hangzhou Normal University (Approval No.: 2024013). All the participants will sign an informed consent form before participating in the survey. The corresponding results and conclusions will be disseminated in journals and conferences after the completion of the study.
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(This article belongs to the Special Issue Shared Decision-Making in Healthcare)
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Open AccessArticle
The Mediating Roles of Lung Function Traits and Inflammatory Factors on the Associations between Measures of Obesity and Risk of Lower Respiratory Tract Infections: A Mendelian Randomization Study
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Xiaofeng Ma, Pan-Pan Zhu, Qian Yang, Yangbo Sun, Chun-Quan Ou and Li Li
Healthcare 2024, 12(18), 1882; https://doi.org/10.3390/healthcare12181882 - 20 Sep 2024
Abstract
Background: Identifying mediators between obesity-related traits and lower respiratory tract infections (LRTIs) would inform preventive and therapeutic strategies to reduce the burden of LRITs. We aimed to recognize whether lung function and inflammatory factors mediate their associations. Methods: We conducted a two-step, two-sample
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Background: Identifying mediators between obesity-related traits and lower respiratory tract infections (LRTIs) would inform preventive and therapeutic strategies to reduce the burden of LRITs. We aimed to recognize whether lung function and inflammatory factors mediate their associations. Methods: We conducted a two-step, two-sample Mendelian randomization (MR) analysis. Two-sample MR was performed on (1) obesity-related traits (i.e., body mass index [BMI], waist circumference [WC], and waist-to-hip ratio [WHR]) and LRTIs (i.e., acute bronchitis, acute bronchiolitis, bronchiectasis, influenza, and pneumonia), (2) obesity-related traits and potential mediators, and (3) potential mediators and LRTIs. Next, two-step MR was applied to infer whether the mediation effects exist. Results: We found that C-reactive protein (CRP), interleukin-6 (IL-6), and forced expiratory volume in the first second (FEV1) mediated 32.59% (95% CI: 17.90%, 47.27%), 7.96% (95% CI: 1.79%, 14.14%), and 4.04% (95% CI: 0.34%, 7.74%) of the effect of BMI on pneumonia, and they mediated 26.90% (95% CI: 13.98%, 39.83%), 10.23% (95% CI: 2.72%, 17.73%), and 4.67% (95% CI: 0.25%, 9.09%) of the effect of WC on pneumonia, respectively. Additionally, CRP, forced vital capacity (FVC), and FEV1 mediated 18.66% (95% CI: 8.70%, 28.62%), 8.72% (95% CI: 1.86%, 15.58%), and 8.41% (95% CI: 2.77%, 14.06%) of the effect of BMI on acute bronchitis, and they mediated 19.96% (95% CI: 7.44%, 32.48%), 12.19% (95% CI: 2.00%, 22.39%), and 12.61% (95% CI: 2.94%, 22.29%) of the effect of WC on acute bronchitis, respectively. Conclusions: Health interventions linked to reducing inflammation and maintaining normal lung function could help mitigate the risk of obesity-related LRTIs.
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(This article belongs to the Special Issue The Relationship between Eating Habits, Obesity and Diabetes)
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Open AccessArticle
Translation, Cross-Cultural Adaptation and Validation of the Lymphedema Quality of Life Questionnaire (LYMQOL) in German-Speaking Patients with Upper Limb Lymphedema
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Torsten Schulz, Mary Lee Warg, Simon Heister, Kristin Lidzba, Günce Ciklatekerlio, Yasmin Molter, Stefan Langer and Rima Nuwayhid
Healthcare 2024, 12(18), 1881; https://doi.org/10.3390/healthcare12181881 - 20 Sep 2024
Abstract
Objectives: The LYMQOL is the most frequently translated, validated, objective tool for assessing Health-Related Quality of Life (HRQoL) in individuals with upper limb lymphedema (ULL). There have been adaptations and validations in a number of different countries. While a German version of LYMQOL
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Objectives: The LYMQOL is the most frequently translated, validated, objective tool for assessing Health-Related Quality of Life (HRQoL) in individuals with upper limb lymphedema (ULL). There have been adaptations and validations in a number of different countries. While a German version of LYMQOL Leg for lower limb lymphedema is available, a validated translation of LYMQOL Arm to German is lacking. We aimed to perform a cross-cultural adaption and translation according to ISPOR principles. Methods: Patients suffering from ULL from Germany, Austria, and Switzerland (n = 52) were questioned twice using the translated LYMQOL Arm, SF-36, and an evaluation questionnaire. The assessment of the content validity and face validity proved this version of LYMQOL Arm to be acceptable for interviewing German-speaking patients with ULL in Germany. Results: Comparison of LYMQOL Arm and SF-36 demonstrated good construct validity. Test–retest reliability was moderate to good (intraclass correlation coefficients 0.66–0.73). Cronbach’s alpha values varied between 0.79 and 0.89 in both interviews, indicating good internal consistency. Factor analysis revealed a cumulative variance of 59.5% for the four domains of the questionnaire. Conclusion: There was no significant association between lymphedema stage and LYMQOL Arm score. This trial tested the appropriateness of the German version of the LYMQOL Arm for measuring HRQoL in German-speaking individuals with ULL.
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Open AccessSystematic Review
The Effectiveness of Nonpharmacological Interventions in the Management of Chemotherapy Physical Side Effects: A Systematic Review
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Valentina Elisabetta Di Mattei, Gaia Perego, Francesca Milano and Francesca Gatti
Healthcare 2024, 12(18), 1880; https://doi.org/10.3390/healthcare12181880 - 19 Sep 2024
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Background: Despite advancements in cancer treatment, chemotherapy side effects significantly impact patients both physically and emotionally. While pharmacological treatments can mitigate these side effects, they may trigger additional side effects, exacerbating the overall discomfort experienced by patients; moreover, psychological factors influencing physical symptoms
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Background: Despite advancements in cancer treatment, chemotherapy side effects significantly impact patients both physically and emotionally. While pharmacological treatments can mitigate these side effects, they may trigger additional side effects, exacerbating the overall discomfort experienced by patients; moreover, psychological factors influencing physical symptoms are beyond the reach of pharmacological interventions. Nonpharmacological interventions, however, offer the potential for complementary or alternative solutions. Objectives: This review aims to offer a comprehensive analysis of the literature on the effectiveness of nonpharmacological interventions in managing the physical side effects of chemotherapy. Methods: This review, based on a search of PubMed, PsycINFO, and Web of Science databases, identified 46 relevant studies. It categorizes interventions and evaluates their effectiveness in managing common chemotherapy side effects (fatigue, nausea, pain, diarrhea, and constipation). Results: Guided imagery, tailored exercises, and Qigong show promise in reducing fatigue, while interventions like yoga and cognitive-behavioral approaches address nausea and vomiting. Pain benefits result from guided imagery and educational interventions. Limited evidence exists for diarrhea and constipation interventions, necessitating further research. Conclusions: This review offers provisional conclusions, emphasizing the potential of integrating evidence-based nonpharmacological approaches alongside pharmacological interventions to enhance patient outcomes and reduce chemotherapy-induced side effects, considering factors such as accessibility, safety, customization, and adaptability in clinical settings.
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Open AccessArticle
Association between Multi-Domain Lifestyle and Objective Cognitive Impairment in Elderly People with SCD and MCI in Chinese Communities
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Yuqin Sun, Ruifen Zhang, Zhiqun Mao, Jiajun Yin, Yuanyuan Zhou and Yue Wu
Healthcare 2024, 12(18), 1879; https://doi.org/10.3390/healthcare12181879 - 19 Sep 2024
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Objectives: Controlling the lifestyle associated with dementia risk can delay the process of cognitive decline. Subjective cognitive decline (SCD) and mild cognitive impairment (MCI) are early states in the development of dementia and are also the window period for early intervention in dementia.
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Objectives: Controlling the lifestyle associated with dementia risk can delay the process of cognitive decline. Subjective cognitive decline (SCD) and mild cognitive impairment (MCI) are early states in the development of dementia and are also the window period for early intervention in dementia. The purpose of this study was to explore the association between multi-domain lifestyle and objective cognitive impairment in elderly people with SCD and MCI in Chinese communities and to provide reference for effective implementation of precise health management measures to reduce the risk of dementia. Methods: A total of 265 middle-aged and elderly volunteers recruited from the community were divided into SCD group (107 cases), MCI group (80 cases), and healthy control (HC) group (78 cases). All participants received clinical interview, examination, and cognitive assessments. Results: The total Dementia Risk Reduction Lifestyle Scale (DRRLS) scores in the HC, SCD, and MCI groups [110.00 (11.25) vs. 101.00 (10.00) vs. 79.50 (20.75)] exhibited statistically significant differences among them. The total score of the DRRLS showed a significant negative correlation with the Trail-Making Test (TMT), and significant positive correlations with both the Verbal Fluency Test (VFT) and Auditory Verbal Learning Test (AVLT) scores (p < 0.05). After adjusting for confounding factors, such as age and years of education, multiple linear regression analysis revealed several points. In the SCD group, brain-strengthening exercise and interpersonal relationship scores were negatively correlated with TMT scores (β = −11.257, −15.077; all p < 0.05), while health responsibility, smoking control behavior, and interpersonal relationship scores were positively correlated with AVLT scores (β = 0.485, 0.344, and 0.406; all p < 0.05). In the MCI Group, brain-strengthening exercise, brain-healthy diet, and interpersonal relationship were negatively correlated with TMT (β = −22.011, −16.206, −11.696; all p < 0.01), whereas health responsibility, mental activity, smoking control behavior, interpersonal relationship, and stress management were positively correlated with AVLT (β = 0.450, 0.435, 0.308, 0.256, 0.607; all p < 0.05). Conclusions: In Chinese communities, the unhealthy lifestyle of elderly individuals with SCD and MCI is significantly associated with cognitive function impairment. The greater their unhealthy lifestyle habits, the more pronounced the scope and severity of cognitive function impairment becomes. Furthermore, different dimensions of lifestyle have varying impacts on cognitive domains.
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Open AccessArticle
Association of Tai Chi and Square Dance with Cognitive Function in Chinese Older Adults
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Xiaoguang Zhao, Dongxue Liu and Jin Wang
Healthcare 2024, 12(18), 1878; https://doi.org/10.3390/healthcare12181878 - 19 Sep 2024
Abstract
Objective: This study explores the association of Tai Chi and square dance with cognitive function and compares the effects of the two fitness programs on cognitive function in Chinese older adults. Methods: A total of 1732 older people (aged 60 years and over)
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Objective: This study explores the association of Tai Chi and square dance with cognitive function and compares the effects of the two fitness programs on cognitive function in Chinese older adults. Methods: A total of 1732 older people (aged 60 years and over) met the inclusion criteria from the 2018 Chinese Longitudinal Healthy Longevity Survey. Based on the frequency of participating in Tai Chi and square dance, older adults were divided into three groups: a Tai Chi group (n = 234), a square dance group (n = 345), and a control group (n = 1153). Cognitive function was measured using a modified Mini-Mental State Examination (MMSE). Participation in Tai Chi or square dance was investigated by asking the subjects to report how often they participated in the fitness programs. Results: Older adults in both the Tai Chi group and the square dance group had higher scores in all MMSE items, including orientation, registration, attention and calculation, recall, and language, compared to those in the control group. But there were no significant differences in any MMSE items between the Tai Chi group and the square dance group. Multiple regression analysis showed that participating in Tai Chi or square dance, age, educational level, and sex can predict cognitive function in older people. Conclusion: Our findings suggest that participating in Tai Chi and square dance are associated with better cognitive function, and Tai Chi and square dance have similar effects on cognitive function in the Chinese older population.
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(This article belongs to the Topic Effects of Exercise Behavior and Amount of Exercise on Public Health: How to Overcome Barriers to Increase Adherence)
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Open AccessArticle
Assessment of General Population Understanding and Awareness of Drug Addiction before and after a Health Educational Campaign in Taif City, Saudi Arabia
by
Mohammad S. Alzahrani, Huriyyah A. Alotaibi, Shahad M. Alhumayani, Hadeel F. Aljuaid, Refah S. Alghamdi and Yusuf S. Althobaiti
Healthcare 2024, 12(18), 1877; https://doi.org/10.3390/healthcare12181877 - 19 Sep 2024
Abstract
Objectives: An awareness campaign was carried out in Taif City to increase awareness about substance abuse and its dangers. This study sought to evaluate the effectiveness of the campaign in enhancing the study participants’ awareness and knowledge about drug addiction. Methods: Using pre-
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Objectives: An awareness campaign was carried out in Taif City to increase awareness about substance abuse and its dangers. This study sought to evaluate the effectiveness of the campaign in enhancing the study participants’ awareness and knowledge about drug addiction. Methods: Using pre- and post-campaign surveys, we assessed the campaign’s impact on participants’ understanding of drug addiction. The survey included demographic items, followed by 12 items for awareness, rated on a 5-point Likert scale, with the total scores ranging up to 60. Results: A total of 146 visitors, with a mean age of 33.4 years (SD = 9.2), completed both the pre- and post-questionnaires. Notably, in the post-campaign, 47.3% of the participants acknowledged the risk of IV drug-related infections, a substantial increase from 28.1% from the pre-campaign. Overall, the mean total awareness score increased significantly, from 47.4 (SD = 6.6) pre-campaign to 50.4 (SD = 6.4) post-campaign (paired t = −4.052, p < 0.001). Conclusion: These findings highlight the potential of such campaigns to significantly improve understanding and awareness of drug addiction.
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(This article belongs to the Special Issue Addiction, Substance Use, and Mental Illness: A Public Health Perspective)
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Open AccessSystematic Review
Effectiveness of Mindfulness-Based Interventions with Respect to Psychological and Biomedical Outcomes in Young People with Type 1 Diabetes: A Systematic Review
by
Tamara Gutiérrez-Domingo, Naima Z. Farhane-Medina, Joaquín Villaécija, Sebastián Vivas, Carmen Tabernero, Rosario Castillo-Mayén and Bárbara Luque
Healthcare 2024, 12(18), 1876; https://doi.org/10.3390/healthcare12181876 - 19 Sep 2024
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Background: Type 1 diabetes is a chronic disease especially affecting young people. Mindfulness-based psychological interventions might reduce emotional symptoms post-diagnosis, but the evidence is limited. Objectives: This systematic review aimed to evaluate the effectiveness of mindfulness interventions on psychological well-being and biomedical variables
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Background: Type 1 diabetes is a chronic disease especially affecting young people. Mindfulness-based psychological interventions might reduce emotional symptoms post-diagnosis, but the evidence is limited. Objectives: This systematic review aimed to evaluate the effectiveness of mindfulness interventions on psychological well-being and biomedical variables in young people with type 1 diabetes. Methods: A systematic review of trials was conducted that involved a bibliographic search in electronic databases (Web of Science, MEDLINE, SciELO, Scopus, PsycINFO, and Cochrane Library) considering studies published between 2013 and 2024. Results: A total of 434 records were identified, of which 252 underwent selection according to title and abstract, leaving 32 that were evaluated for eligibility and 7 included in this review. From Google Scholar, six more studies were identified and evaluated, and two were selected. Finally, nine studies were subjected to full reading and a detailed analysis of the inclusion criteria. A total of 66.6% of the studies were evaluated as having a methodological quality of moderate or optimal, but the samples analysed tended to be small, and only two articles carried out short-term follow-up evaluations. Conclusions: Mindfulness-based interventions, upon reviewing the preliminary results, may be posited as a viable strategy to enhance psychological (anxiety, diabetes distress, perceived stress, depression, self-efficacy, psychological well-being, and quality of life) and biomedical outcomes (glycaemic control, blood glucose levels, and diastolic blood pressure) for type 1 diabetes in young people. Although promising, further research is required to improve the quality, methodology, and design of studies.
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Open AccessArticle
The Prevalence of Chronic Interosseous Membrane Lesions Following Mason II and III Radial Head Fractures in Complex Elbow Instability—A Retrospective Observational Cohort Study
by
Giuseppe Giannicola, Luca Di Sante, Giulia Corsi, Carmine Zoccali, Sebastien Prigent, Gianluca Cinotti and Pasquale Sessa
Healthcare 2024, 12(18), 1875; https://doi.org/10.3390/healthcare12181875 - 19 Sep 2024
Abstract
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Purpose: The primary aim of the present study was to assess the prevalence of chronic lesions of the central band of the interosseous membrane (cbIOM) in complex elbow instability (CEI) in a consecutive series of patients who had previously undergone surgical treatment for
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Purpose: The primary aim of the present study was to assess the prevalence of chronic lesions of the central band of the interosseous membrane (cbIOM) in complex elbow instability (CEI) in a consecutive series of patients who had previously undergone surgical treatment for Mason II and III radial head (RH) fractures. The secondary aim was to define its clinical significance. Methods: We performed a retrospective study on a prospective database. Our study population comprised 93 patients affected by CEI with type II or III RH fractures according to Mason’s classification who were analyzed in the chronic setting. All patients were treated according to the current therapeutic algorithms. At the last follow-up, the “muscular hernia sign” was investigated by means of a bilateral ultrasonographic examination to assess any chronic cbIOM lesions; the Mayo Elbow Performance Score (MEPS) was used to evaluate the clinical significance of these lesions. Results: All 93 patients were assessed after a mean time of 7.3 years (range: 2–12). No positive “hernia signs” were found, while five patients (5.4%) displayed an increased laxity of the cbIOM when compared with the contralateral side despite a negative “hernia sign”. The clinical outcome in all five patients was excellent with a mean MEPS of 96 (range, 90–100). Conclusions: Chronic cbIOM lesions are very rare in CEI with RH fractures. No patients in this large sample displayed a cbIOM complete lesion; in cases with increased laxity, satisfactory mid-term clinical results were observed. Considering that previous studies reported (1) a high prevalence of cbIOM lesions in patients with Mason II and III RH fractures and (2) the current expert opinion about the scarce healing potential of the cbIOM, this study also suggests that the IOM may heal better than previously believed when RH fractures are treated appropriately in the acute setting.
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Open AccessSystematic Review
Perinatal Exposure to Tobacco Smoke and Its Association with the Maternal and Offspring Microbiome: A Systematic Review
by
Eleni Falara, Dimitra Metallinou, Christina Nanou, Maria Vlachou and Athina Diamanti
Healthcare 2024, 12(18), 1874; https://doi.org/10.3390/healthcare12181874 - 19 Sep 2024
Abstract
Background: The human microbiome, comprising trillions of microorganisms, significantly influences human health and disease. During critical periods like the perinatal phase, the microbiome undergoes significant changes, impacting lifelong health. Tobacco smoke, a known environmental pollutant, has adverse effects on health, particularly during pregnancy.
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Background: The human microbiome, comprising trillions of microorganisms, significantly influences human health and disease. During critical periods like the perinatal phase, the microbiome undergoes significant changes, impacting lifelong health. Tobacco smoke, a known environmental pollutant, has adverse effects on health, particularly during pregnancy. Despite this, its association with the perinatal microbiome remains understudied. Methods: We conducted a systematic review to integrate findings on perinatal tobacco smoke exposure and its association with the maternal and neonatal microbiomes. We conducted a comprehensive literature search in the PubMed, Scopus, and Web of Science databases from January 2000 to February 2024. We selected studies that met predefined inclusion criteria and performed data extraction. Results: The review included eight studies that revealed diverse associations of perinatal tobacco exposure with the maternal and neonatal microbiome. Active smoking during pregnancy was linked to alterations in microbiome composition and diversity in children. Maternal smoking correlated with increased Firmicutes abundance and decreased Akkermansia muciniphila abundance in offspring. Additionally, exposure to thirdhand smoke in neonatal intensive care units was related to infant microbiome diversity. Infants exposed to tobacco smoke showed various microbial changes, suggesting potential implications for childhood health outcomes, including obesity risk. Conclusions: Perinatal exposure to tobacco smoke exerts significant influence on the maternal and neonatal microbiomes, with potential implications for long-term health outcomes. Addressing socioeconomic and psychological barriers to smoking cessation, implementing stricter smoking regulations, and promoting public health campaigns are essential steps towards reducing tobacco-related harm during the perinatal period. Further longitudinal studies and standardized assessment methods are needed to validate these findings and guide the development of effective preventive measures.
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(This article belongs to the Special Issue Midwifery Care: Improvement of Maternal and Newborn Health)
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Open AccessArticle
Categorising Subjective Perceptions of Middle-Aged Breast Cancer Patients Using Q Methodology
by
Min-Jeung Shim, Song-Yi Lee and Oh-Sun Ha
Healthcare 2024, 12(18), 1873; https://doi.org/10.3390/healthcare12181873 - 18 Sep 2024
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Background/Objectives: This study explores the characteristics of different perception types in middle-aged female breast cancer patients and proposes psychological counselling interventions tailored to each type. Methods: The study used the Q methodology, starting with the construction of 40 Q samples and 39 P
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Background/Objectives: This study explores the characteristics of different perception types in middle-aged female breast cancer patients and proposes psychological counselling interventions tailored to each type. Methods: The study used the Q methodology, starting with the construction of 40 Q samples and 39 P samples. Results: We categorised middle-aged female patients’ subjective perceptions of battling breast cancer into five types along a spectrum: Type 1, ‘Embracing a New Life’; Type 2, ‘Finally Focusing on Myself’; Type 3, ‘Struggling Amidst Confusion’; Type 4, ‘Withdrawing in Despair’; and Type 5, ‘Pushed to the Edge of Fear’. Conclusions: This study revealed that the subjective experiences of middle-aged female breast cancer patients range on a spectrum from post-traumatic growth to post-traumatic stress disorder (PTSD). Based on these findings, this study discusses the characteristics and significance of each subjectivity type and suggests implications and directions for future research.
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Open AccessArticle
Development of an AI-Based Predictive Algorithm for Early Diagnosis of High-Risk Dementia Groups among the Elderly: Utilizing Health Lifelog Data
by
Ji-Yong Lee and So Yoon Lee
Healthcare 2024, 12(18), 1872; https://doi.org/10.3390/healthcare12181872 - 18 Sep 2024
Abstract
Background/Objectives: This study aimed to develop a predictive algorithm for the early diagnosis of dementia in the high-risk group of older adults using artificial intelligence technologies. The objective is to create an accessible diagnostic method that does not rely on traditional medical equipment,
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Background/Objectives: This study aimed to develop a predictive algorithm for the early diagnosis of dementia in the high-risk group of older adults using artificial intelligence technologies. The objective is to create an accessible diagnostic method that does not rely on traditional medical equipment, thereby improving the early detection and management of dementia. Methods: Lifelog data from wearable devices targeting this high-risk group were collected from the AI Hub platform. Various indicators from these data were analyzed to develop a dementia diagnostic model. Machine learning techniques such as Logistic Regression, Random Forest, LightGBM, and Support Vector Machine were employed. Data augmentation techniques were applied to address data imbalance, thereby enhancing the model performance. Results: Data augmentation significantly improved the model’s accuracy in classifying dementia cases. Specifically, in gait data, the SVM model performed with an accuracy of 0.879. In sleep data, a Logistic Regression was performed, yielding an accuracy of 0.818. This indicates that the lifelog data can effectively contribute to the early diagnosis of dementia, providing a practical solution that can be easily integrated into healthcare systems. Conclusions: This study demonstrates that lifelog data, which are easily collected in daily life, can significantly enhance the accessibility and efficiency of dementia diagnosis, aiding in the effective use of medical resources and potentially delaying disease progression.
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(This article belongs to the Special Issue Smart and Digital Health)
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Open AccessProtocol
Psychosocial Impacts of Idiopathic Clubfoot on Parents and Children: A Scoping Review Protocol
by
Nurhanis Syazni Roslan, Syurahbil Abdul Halim, Ismail Munajat and Sarina Sulong
Healthcare 2024, 12(18), 1871; https://doi.org/10.3390/healthcare12181871 - 18 Sep 2024
Abstract
Background/Objectives: Idiopathic clubfoot is a complex pediatric foot deformity. The Ponseti technique is widely regarded as the standard for correcting deformities, and treatment compliance is essential for preventing relapse. Examining psychosocial effects on parents and/or children during clubfoot treatment provides valuable insights for
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Background/Objectives: Idiopathic clubfoot is a complex pediatric foot deformity. The Ponseti technique is widely regarded as the standard for correcting deformities, and treatment compliance is essential for preventing relapse. Examining psychosocial effects on parents and/or children during clubfoot treatment provides valuable insights for improving compliance. This scoping review will map the existing literature on the psychological and social effects experienced by parents and/or children with idiopathic clubfoot. It also aims to examine the assessment tools used to measure these impacts and identify factors influencing treatment compliance. Methods: This review will adhere to the Joanna Briggs Institute (JBI) guidelines for scoping reviews. The search will include databases such as Scopus, Web of Science, EBSCOhost, MEDLINE, and PsycINFO and focus on studies published in the last 10 years. This review will include quantitative, qualitative, and mixed-method studies that investigate the psychological and social effects experienced by parents or affected children of any age with idiopathic clubfoot. Reporting will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISM-ScR) extension guidelines. The screening and data extraction process will involve two independent reviewers. The analysis will be descriptive and qualitative. Results: The findings will be presented in tables and a narrative summary. Conclusion: This review may guide health practitioners in developing evidence-based interventions to improve treatment adherence.
Full article
(This article belongs to the Special Issue New Insights into Children’s Orthopedic Health)
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