Insights into Antioxidant Compounds: From Extraction to Mechanism of Action

Dear Colleagues,

Antioxidant compounds have emerged as compounds of significant value due to their ability to counteract oxidative stress, a major cause underlying numerous chronic diseases and aging. As researchers and industries increasingly explore the potential health benefits of antioxidants, it has become imperative to comprehensively investigate both methods for their extraction and the intricate molecular mechanisms driving their activity. The extraction of antioxidant compounds from diverse natural sources, such as plants, fruits, and vegetables, is a dynamic field that holds promise for yielding potent bioactive compounds. Innovative extraction approaches have demonstrated the possibility of enhancing the efficiency of extracting antioxidants while preserving their biological activity.

At the molecular level, the mechanisms by which antioxidant compounds exert their protective effects against oxidative stress remain a trending topic of research. These mechanisms encompass a range of interactions, including the scavenging of reactive oxygen species (ROS), modulation of signaling pathways, etc. By investigating such mechanisms, researchers can uncover the precise ways in which antioxidants counteract oxidative damage, thus paving the way for novel therapeutic interventions.

This Special Issue provides an opportunity for researchers to dive into the intricate world of antioxidants, spanning from innovative extraction techniques to unraveling their mechanisms of action at the molecular level. Authors are encouraged to contribute articles with a focus on extraction techniques that also consider the intriguing molecular mechanisms that drive antioxidant activity. We encourage studies that encompass a wide array of antioxidant compounds, from polyphenols and flavonoids to vitamins and enzymes. By shedding light on these aspects, we aim to enrich our understanding of how antioxidants can be harnessed for therapeutic applications, ultimately contributing to enhanced health and well-being.

Dr. Theodoros G. Chatzimitakos
Guest Editor

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• antioxidants
• oxidative stress
• extraction methods
• bioactive compounds
• molecular mechanisms
• reactive oxygen species (ROS)
• signaling pathways
• therapeutic applications