Advanced Research on Obesity and Cancer

Dear Colleagues,

Obesity is clearly related to many types of cancer, but the precise molecular mechanisms remain largely unknown. Does excess body fat/energy intake somehow trigger a normal cell to become malignant, or do fat-produced substances promote growth of malignant cells induced by other carcinogens? Conversely, perhaps some adipokine induces malignant change, and chronic caloric excess is a promoter? What is the exact role of the many molecular processes induced by obesity, including alterations in signaling pathways (p53, Notch, Wnt, and others)? What are the major adipokines driving cancer, and can these be altered by lifestyle chances or drugs?

This Special Issue will explore these and other questions. Appropriate topics include the role of excess calories in cancer as well as the specific activities of various adipokines in the malignant process. Novel hypotheses in these and other areas are needed and welcome. Precise information on the fat–cancer connection should stimulate important cancer prevention and treatment clinical research. When considering your submission, please keep in mind that IJMS is a journal of molecular science. Therefore, pure clinical studies will not be suitable for our journal. However, submissions of clinical studies that include biomolecular experiments or pathological research with case sample data are welcomed.

All authors are invited to send their research related to the topic of our Special issue, both original and review articles, to be assessed and included in the peer-review process of our journal.

Dr. Daniel W. Nixon
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• obesity
• body fat
• cancer
• adipokines
• leptin
• adiponectin
• angiogenesis
• molecular activity
• signaling pathways