New Insights into Viral Vector Mediated Gene Therapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: closed (30 August 2024) | Viewed by 242
Special Issue Editor
Special Issue Information
Dear Colleagues,
In the past decade, viral vector-mediated gene therapy has shown their potential for the treatment of inherited disorders. With 26 gene therapy products approved worldwide, including genetically modified cell therapies, viral vectors are now used for the treatment of retinal, metabolic or neurodegenerative diseases, as well as cancer. While oncolytic, lentiviral, adenoviral or adeno-associated viral vectors have their own advantages, some limitations related to production capacity, tissue targeting, vector integration, immunogenicity or toxicity remain challenging.
This Special Issue of IJMS invites submissions of original research or review articles addressing recent developments in viral vectors for gene therapy, including vector design and production, vector–cell interactions, and proof-of-concept in preclinical models, as well as innovative strategies to prevent vector-mediated toxicity.
Dr. Gwladys Gernoux
Guest Editor
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Keywords
- viral vector
- gene therapy
- gene delivery
- adenovirus
- adeno-associated virus
- lentivirus
- analytics
- preclinical testing
- inherited disorders
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