GSK3 as a Master Regulator of Cellular Processes, 2nd Edition

Dear Colleagues,

Glycogen synthase kinase (GSK) 3α and β are key proteins targeting a plethora of molecules and regulating various cellular processes thus steering central functions such as metabolism, proliferation, differentiation, apoptosis, adhesion, and migration. In consequence, GSK3 activity has to be tightly controlled to ensure the regulated course of cellular development and behavior whilst dysregulations may result in a variety of disorders such as neurological/neurodegenerative, metabolic, and inflammatory diseases, or different forms of cancer. Decades of research provided profound knowledge on the activity, regulation, and function of the GSK3 paralogues during physiological as well as pathophysiological events. In many biological contexts, however, GSK3 appears to mediate unexpected, in part even conflicting effects. Thus, its specific behavior in a particular situation (e.g., during infections or cancer) is often difficult to predict and its role is still controversially discussed. This Special Issue aims at further elucidating the modulation of GSK3α and β under various conditions and their role in controlling multiple processes within the cell. We cordially invite you to submit a respective manuscript; all types of papers (research articles, brief reports, reviews, hypotheses, case reports, communications) are welcome.

More published papers could be found in the closed Special Issue: GSK3 as a Master Regulator of Cellular Processes

Prof. Dr. Ralf Lichtinghagen
Dr. René Huber
Guest Editors

Manuscript Submission Information

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