Multiple Myeloma: Molecular Mechanisms and Targeted Therapy, 2nd Edition

Dear Colleagues,

Multiple myeloma (MM) is a plasma cell disorder characterised by bone marrow infiltration with clonal plasma cells, which secrete monoclonal immunoglobulin detectable in serum and/or urine. The development of novel targeted therapies has markedly improved response rates and survival outcomes, but MM still remains incurable.

While novel agents have improved treatment outcomes, the identification of biomarkers that will facilitate clinicians to determine which treatment is optimal is a crucial area in the clinical management of MM. The availability of predictive biomarkers would be useful in avoiding ineffective treatments and allow for the administration of alternative regimens that are continuing to be approved for the treatment of MM.

Since Volume 1 of the “Multiple Myeloma: Molecular Mechanism and Targeted Therapy” Special Issue was successful, we have reopened it again for the International Journal of Molecular Sciences (ISSN: 1422-0067, IF: 5.6, JCR Category Q1). In this Special Issue, we welcome contributions on all aspects of pathobiology, symptoms, diagnostic tool and biomarker development, and novel treatment options of MM.

Dr. Paul Dowling
Dr. Despina Bazou
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• multiple myeloma
• biomarkers
• tumour microenvironment
• genomics
• proteomics
• extramedullary myeloma
• therapy
• minimal residual disease
• smouldering myeloma