Molecular Insights into Dental Materials and Oral Disease

Dear Colleagues,

Oral diseases, disorders, and pathological states of the mouth cavity affect people of different ages and have a negative impact on human health. It is evident that newly developed dental materials and biomaterials will improve oral health. These components can have different purposes, ranging from encouraging osteogenesis to inhibiting the formation of bacterial biofilms.

The primary purposes of dental biomaterials were to support masticatory loads mechanically (e.g., dental crowns) or to exhibit optical qualities that would allow them to appear pleasing and natural (e.g., resin composites). Over the years, many clinically used materials, including sealants, orthodontic adhesives, cements, and hybrid materials, have been used with technologies such as CAD-/CAM-based restorative dentistry to improve patients’ quality of life. These are called biomaterials because they have important interactions with oral biology and molecular processes.

It is critical to reevaluate the molecular mechanisms behind the development and maintenance of oral health and analyze the findings of studies on the anatomical, functional, and molecular changes of the masticatory function, analyzing the interaction with the materials that are used to treat oral conditions.

The aim of this Special Issue is to promote research on the pathophysiology and microbiology of oral diseases, in particular in relation to biomaterials adopted in the field.

Prof. Dr. Giuseppe Marzo
Guest Editor

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• oral diseases
• biomaterials
• resin composites
• masticatory function
• osteogenesis