Protein–RNA Interactions: Function, Mechanism, and Identification

Dear Colleagues,

Protein–RNA interactions (PRIs) are fundamental to all cellular processes, playing a critical role in gene expression, RNA processing, and protein synthesis. These interactions are mediated by RNA-binding proteins (RBPs) that recognize specific RNA targets through their sequences, structures, and modifications. Understanding these interactions is essential for deciphering the complex regulatory networks that govern cellular function.

We are pleased to invite you to submit your work to this Special Issue of IJMS focused on the intricate interplay between proteins and RNA molecules. This Special Issue aims to delve into the multifaceted functions and mechanisms underlying PRIs, while also showcasing innovative techniques for their identification.

In this Special Issue, original research articles and reviews are welcome. Topics of interest include, but are not limited to, the following:

• Functional roles of RBP-RNA interactions in gene expression regulation;
• Mechanisms governing protein–RNA recognition and RBP specificity;
• Experimental and computational methodologies for identifying PRIs;
• The impact of PRIs on RNA processing, stability, and translation;
• The dysregulation of PRIs in human diseases and development;
• Therapeutic strategies targeting aberrant PRIs.

Looking forward to receiving your contributions.

Dr. Alessio Colantoni
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• RNA-binding protein (RBP)
• protein–RNA interaction
• RNA structure
• RNA processing
• RNA stability
• RNA modification
• translation
• gene regulatory network