New Insights into the Effects of Microbiome-Derived Metabolites on Health and Disease

Dear Colleagues,

The biological impacts of molecules derived from gut bacteria are apparent in diverse tissues, constituting a crucial facet of the gut microbiome’s impact on our health. Metabolites such as short-chain fatty acids, methylamines, and various others intricately modulate carbohydrate metabolism and cardiovascular homeostasis and influence the course of numerous diseases. Furthermore, factors such as gut–blood barrier permeability, liver metabolism, and kidney clearance may influence metabolite concentrations, thereby limiting their effects.

This Special Issue endeavours to establish a platform for research on the molecular biological effects of bacterial metabolites and the pathways responsible for these impacts. Additionally, we extend an invitation for studies elucidating disease-associated mechanisms that shape the manifestations of bacterial metabolites.

Dr. Kinga Jaworska
Guest Editor

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• bacterial metabolites
• short-chain fatty acids
• trimethylamine N-oxide
• gut microbiome
• molecular pathways
• intestinal barrier