Molecular Mechanisms and Targeted Therapies of Breast Cancer

Dear Colleagues,

Breast cancer is the most common malignancy in women and is a serious public health challenge. Current research focuses on searching for new markers that will allow us to understand the molecular mechanisms of individual breast cancer cell subtypes. The molecular profile of breast cancer cells allows for the development of personalized therapy. Although targeted therapies are more effective and specific than classic therapeutic pathways, they are also associated with the development of molecular resistance. The combination of classic clinical and histopathological tests with omics allows the development of new therapeutic strategies combining classic chemotherapy and immunotherapy with other innovative forms of treatment.

This special issue is open to submission of research articles on molecular aspects of the biology of breast cancer, including diagnostic, prognostic, and predictive biomarkers. The aim of this special issue is to collect the latest knowledge on the signaling pathways involved in the proliferation, and metastasis of breast cancer cells, intercellular communication, and the role of the tumor microenvironment. In addition, we expect work in the areas of genomics, transcriptomics, and epigenetics in the aspect of molecularly targeted therapies. We invite original research and review papers describing the latest achievements and perspectives in this field.

Prof. Dr. Piotr Dzięgiel
Dr. Karolina Jabłońska
Dr. Katarzyna Nowińska
Guest Editors

Manuscript Submission Information

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• breast cancer
• cancer progression
• cancer metastasis
• tumor microenvironment
• molecular mechanisms
• molecular markers
• epigenetics
• genomics
• transcriptomics
• EMT
• targeted therapies
• signaling pathways
• exosomes
• EMT
• hormonal regulation
• drugs
• apoptosis