Cutting-Edge Research and Applications of Extracellular Microvesicles in Disease Management

Dear Colleagues,

Research on extracellular microvesicles (EMVs) at the molecular level is a rapidly advancing field with transformative implications for disease management. EMVs, derived from cells, act as essential mediators in intercellular communication, transporting a diverse array of bioactive molecules. The cargoes of extracellular microvesicles reflect core intracellular processes, and their functional properties may regulate fundamental biological and pathological processes. Their composition, reflecting the physiological state of parent cells, holds significant value for diagnostics and therapies.  In cancer, EMVs stand out as promising biomarkers for early detection and treatment monitoring. Furthermore, their exploration in immune modulation holds potential for treating autoimmune diseases. The capability of EMVs to traverse biological barriers, including the blood–brain barrier, provides opportunities for targeted drug delivery in neurological disorders. In developmental biology, EMVs influence signaling pathways, cell differentiation, and the coordination of developmental events, offering insights into regenerative medicine.

This Special Issue of the International Journal of Molecular Sciences focuses on the molecular research and applications of extracellular microvesicles in disease management, welcoming both original research articles and reviews that address the perspective of highly targeted and personalized therapies, marking a paradigm shift in disease management.

Dr. María Isabel Torres
Guest Editor

Manuscript Submission Information

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• extraccellular microvesicles
• exosome
• ectosoma
• biomarkers
• cargoes of extracellular vesicles
• therapeutics
• diagnosis