COVID-19: Advances in Pathophysiology and Therapeutics

Dear Colleagues,

While the official pandemic status of COVID-19 may have concluded, the impact of the disease, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is far from over. In fact, there are ongoing lessons to be learned and areas of research yet to be explored. The complexity of the disease, from its intricate pathophysiology and wide array of clinical presentations to the multiple therapeutic options available, continues to challenge the medical community. This Special Issue aims to serve as a comprehensive platform for the latest research findings that explore the advances in understanding the pathophysiology and developing new therapeutic interventions for COVID-19.

The objectives of this Special Issue are as follows: firstly, to collate research articles, reviews, and case reports that contribute to an evolving understanding of the immunological mechanisms specific to COVID-19; secondly, to feature evidence-based, clinically relevant updates on available treatment modalities and explore the current pharmacological landscape; and lastly, to facilitate a multidisciplinary discussion that aligns research outcomes with practical clinical applications, including the management of COVID-19 and its associated comorbid conditions.

Topics of interest may include:

Molecular and cellular mechanisms of SARS-CoV-2 infection and immune response underlying COVID-19;

Emerging therapeutic avenues and translational research findings that translate into clinical practice;

Biomarkers for disease severity and prognosis;

Advances in antiviral agents, monoclonal antibodies, and other pharmacotherapeutics;

Therapeutic management of comorbid conditions in COVID-19 patients;

Evaluations on the efficacy of existing and novel treatments.

Dr. Karolina Akinosoglou
Guest Editor

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• COVID-19
• SARS-CoV-2
• pathophysiology
• immunology
• pharmacotherapy
• biomarkers
• comorbidities
• clinical management
• disease severity
• treatment efficacy