Head and Neck Cancer: From Molecular Diagnosis to Targeted Therapy

Dear Colleagues,

Head and neck squamous cell carcinoma (HNSCC) is a pressing concern due to its rising incidence in Europe and worldwide. HNSCCs are aggressive tumors often diagnosed at an advanced stage, posing significant challenges for effective treatment. The current therapeutic options are notably limited and fall short in providing comprehensive solutions.

In recent years, molecular approaches have shown promise for applications in diagnosing and providing implicit therapy for HNSCC. Notably, molecular methods have aimed to classify these tumors based on their anatomical locations, offering potential insights into tailoring treatment strategies.

We invite you, dear colleagues, to contribute to this Special Issue by submitting original research papers, insightful reviews, or concise communications focused on head and neck cancer pathology, diagnosis, and treatment. Manuscripts proposing novel, targeted therapeutic approaches grounded in molecular analyses will be the main focus of the Special Issue.

We firmly believe that, with your invaluable contributions, we can develop a molecular classification for head and neck tumors, a critical element currently absent in the field. Such a classification holds the promise of paving the way for personalized therapies. Furthermore, we hope to identify new molecular therapeutic targets that can be used to stratify these pathologically apparently remarkably uniform tumors.

This Special Issue is being coordinated by Prof. Dr. Marius L. Raica in conjunction with our Guest Editor's assistant Dr. Cristina-Stefania Dumitru [email protected] (Department of Microscopic Morphology/Histology, Angiogenesis Research Center, “Victor Babes” University of Medicine and Pharmacy, Sq. Eftimie Murgu no. 2, 300041 Timisoara, Timis, Romania).

Prof. Dr. Marius L. Raica
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• head and neck cancer
• targeted therapy
• tumor genetics
• biomarkers
• combination therapy
• resistance to therapy