Special Issue in Honor of Prof. Susan Lunte's 65th Birthday: When Microfluidics Meets Pharmacology: From Cell Biology and Toxicology to Drug Discovery and Development

Dear colleagues,

With the present Special Issue, I would like to take the time to honour and celebrate the 65^th birthday of Susan Lunte, a pioneer of microfluidics, currently holding the position of Ralph N. Adams Distinguished Professor of Chemistry and Pharmaceutical Chemistry at the University of Kansas. Over the last three decades she has made a huge impact on the fields of microfluidics, bioanalytical chemistry and biomedical analysis, with a particular focus on microanalytical methods for the investigation of the transport and metabolism of peptides across the blood–brain barrier, separation-based sensors employing on-line microdialysis coupled to microchip electrophoresis, cell-based assays on chips, and microchip-based diagnostics for cardiovascular and metabolic diseases.

Numerous combined systems coupling bi- and three-dimensional in vitro cell culture models with microfluidics have been developed and applied to investigate cell biology and toxicology, as well as drug discovery and development processes, allowing not only the replication of the in vivo environment but also the accurate prediction of the safety profile of drug candidates.

Leading by Dr. Giuseppe Caruso and assisted by Dr. Anna Privitera and Dr. Vincenzo Cardaci (University of Catania), the main aim of this Special Issue, honoring Prof. Lunte’s contribution to the field, is to highlight the huge impact of microfluidics-based technologies in the context of preclinical research.

The submission of original research papers and reviews based on interdisciplinary studies involving the combination of two or more fields, such as pharmacology and biochemistry, and cellular and molecular biology, are welcome. The submission of manuscripts containing data obtained by microfluidic-based technology is strongly encouraged, as are manuscripts focusing on one of the four “Prof. Lunte” topics described above. Those which may not strictly relate to these topics, but open a window to further investigations through microfluidics, will be considered.

Dr. Giuseppe Caruso
Guest Editor

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• Microfluidics
• Pharmacology
• Toxicology
• Drug delivery and development
• Neurotransmitters
• Antioxidants
• Oxidative stress
• Inflammation