Chronic Pain: Diagnosis, Pathophysiological Mechanisms and Treatment

Dear Colleagues,

Chronic pain continues to be one of the most common illnesses, often without effective treatment options. The number of conditions, the concomitant involvement of different systems, and the personal characteristics of patients do not allow for standardized diagnostic and treatment procedures. Increases in human lifespan have certainly also increased the number of people in pain, alongside increases in personal, familial, societal, and economical burden. New drugs and treatments are available, but at present, patients too often go from one treatment to another without any possibility to resolve their pain.

With this Special Issue, we would like to collect evidence clarifying the present state of the art in chronic pain molecular pathology. Articles about the following are welcomed:

• Sex differences in pain syndromes: clinical and laboratory evidence alongside molecular data;
• Molecular mechanisms underlying age differences in pain syndromes: comparative studies in men and women;
• Molecular diagnostic tools: new systems for old illnesses;
• Molecular-based treatment approaches for pain.

Prof. Dr. Anna Maria Aloisi
Prof. Dr. Thomas Herdegen
Guest Editors

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• chronic pain
• sex differences
• age differences
• pain therapies