New Insights into Colorectal Cancer

Dear Colleagues,

Colorectal cancer (CRC) is one of the most common tumors, and the second most common cause of cancer-related deaths worldwide. The management of this type of cancer is typically characterized by a multidisciplinary approach and treatment is increasingly tailored to the patient.

The cause of colorectal cancer must be found using our new knowledge of the biological aspects of the disease. Understanding the complex molecular mechanisms underlying the host immune response in CRC and the molecular classification of the tumor is critical to highlight new CRC biomarkers and guide therapeutic decisions leading to a significant impact on disease outcomes. However, even in the era of molecular medicine and targeted therapies, much remains to be found about the mechanisms that contribute to developing metastatic disease and lead to a poor prognosis. In this context, the aim of this Special Issue “New Insights into Colorectal Cancer” is to further expand our current knowledge in the field of CRC by focusing on recent research involving the molecular mechanisms underlying colorectal carcinoma, including epigenetic changes, interaction with the environment and host immune system, and analysis by omics technologies. Moreover, this Special Issue will discuss the recent discoveries in terms of diagnostic and prognostic biomarkers of CRC.

Dr. Simona Deidda
Guest Editor

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• colorectal cancer
• biomarkers
• inflammatory markers
• diagnosis
• prognosis
• treatment response