Oral Cancer: Update on Molecular Pathology, Mechanisms and Treatments

Dear Colleagues,

Oral cancer is a generic term for the malignant tumors that occur in the stomatognathic region and is characterized as having multiple risk factors. The relationship between the incidence of oral cancer and lifestyle factors, such as diet, smoking tobacco, drinking alcohol, and oral hygiene habits, has been pointed out. Additionally, mechanical stimulation by prosthetic devices also triggers the incidence and development of oral cancer. Moreover, it has recently been reported that periodontitis and periodontopathic bacteria can be individual risk factors for oral cancer development. On the other hand, the oral cavity is covered with mucosal surfaces, consisting of squamous epithelia other than the teeth. Therefore, it also shows that more than 90% of oral cancers are squamous cell carcinomas pathologically. This Special Issue provides an update on the situation of oral cancer (the possible mechanisms of incidence and development, diagnosis, biomarkers, and treatments that are based on the actions of and changes in molecules) from multiple perspectives, such as pathologically, bacteriologically, biochemically, molecularly, and pharmacologically.

Since IJMS is a journal of molecular science, pure clinical studies will not be suitable for our journal; however, clinical submissions that feature biomolecular experiments are welcomed.

Prof. Dr. Norio Sogawa
Guest Editor

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• oral cancer
• mechanisms of incidence and development of oral cancer
• metastasis
• diagnosis
• biomarkers
• treatments (active ingredients, medicines, biomedicines, and gene therapy)