Advances and Insights in Tumorogenesis and Tumor Metastasis

Dear Colleagues,

The interplay of tumorigenesis and metastasis remains one of the most significant challenges in cancer research, further complicated by the multifaceted nature of cancer progression and an incomplete understanding of metastatic processes. Technological advances have illuminated crucial genetic and proteomic variations distinguishing cancerous tissues from their normal counterparts. Despite this development, several obstacles, including a lack of precise molecular mechanisms of tumor metastasis and validated biomarkers, make it difficult to select suitable candidates for clinical trials that effectively target both tumorigenesis and metastasis. Efforts to unravel the precise molecular mechanisms of tumor spread and develop accurate preclinical models are imperative for the careful design of clinical trials to improve patient outcomes. In this Special Issue, we welcome manuscripts aimed at advancing our understanding of the mechanisms behind cancer's initiation and metastasis, uncovering novel molecular targets, as well as the development of accurate preclinical models that may foster clinical trial advancements and navigate therapy development challenges.

Dr. Sayem Miah
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• tumorigenesis
• metastasis
• biomarkers