Advances and Challenges of Molecular Research on Disease in Animal Models in Biomedicine

Dear Colleagues,

Significant advances in our knowledge of animal models have contributed to the innovation of biomedical sciences through a better understanding of pathological, biological, and molecular mechanisms. Through murine, primate, porcine, and aquatic models, several cardiovascular, renal, neurological, behavioral, and oncological disorders are being better understood while developing new therapeutic approaches. They facilitate the development and testing of drugs, vaccines, organ transplants, and surgical techniques applicable to human and veterinary medicine. The broad range of species used in research has implied challenges and brought exponential advances in medicine, especially with the introduction of transgenic animals, and the implementation of nanotechnology and artificial intelligence.

The goal of this Special Issue on “Advances and Challenges of Molecular Research on Disease in Animal Models in Biomedicine” is to better understand novel molecular and therapeutic approaches and signaling molecules for studying pathologies that affect humans by replicating pathophysiological processes.

I want to invite you to submit original research communication and or review manuscripts focused, but not limited to, innovative findings and challenges of animal models contributing to enhancing the comprehensive view of the molecular pathophysiological mechanisms underlying the pathogenesis and progression of cardiovascular, renal, metabolic, oncology, and behavioral diseases. Studies involving animal models from different species are encouraged.

Dr. Minolfa C. Prieto
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• animal models
• cardiovascular disease
• renal disease
• metabolic, neurological, behavioral, and oncological disorders
• pathophysiology
• cell and molecular research