From Basic Science to Treatment Strategies: Personalized Cancer Therapy, 2nd Edition

Dear Colleagues,

As Volume 1 of the Special Issue “From Basic Science to Treatment Strategies: Personalized Cancer Therapy” was successful, we reopen this Special Issue again in the International Journal of Molecular Sciences (ISSN 1422-0067, IF 5.6, JCR Category Q1).

For this Special Issue, we will continue to highlight the recent advances in cancer care in which targeting patient-specific genomic and pathway abnormalities has become the standard of care for the vast majority of cancer patients. For example, we will highlight advances in targeting isocitrate dehydriogenase, fibroblast growth factor receptor, human epidermal growth factor receptor 2, B-raf protooncogene/mitogne-activated protein kinase (BRAF/MEK), claudin, hypoxia-inducible factor, folate-receptor alpha, epidermal growth factor receptor, ROS protooncogene 1 (ROS1), neurotrophic tropomyosin kinase receptor (NTRK), met protooncogene, and others. We will also highlight the use of liquid biopsies to diagnose some of those abnormalities. The use of circulating DNA in cancer patients is being used more and more to determine who needs systemic therapy and for prognostic information.

Dr. Atif Hussein
Guest Editor

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• targeted therapy
• personalized medicine
• immunotherapy
• circulating tumor DNA
• prognosis
• genomic profiling
• liquid biopsies