Mitochondria and Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (25 January 2023) | Viewed by 12010
Special Issue Editor
Interests: mitochondria; bioenergetic function; Warburg effect; mitochondria-targeted cancer chemotherapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The connection between mitochondria and cancer dates back to the 1930s when Otto Warburg first reported his observations of increased rates of aerobic glycolysis in a variety of tumors and hypothesized that this phenomenon might be due to an impaired respiratory capacity in certain cancer cells. Now, nearly a century later, altered energy metabolism is considered an emerging hallmark of cancer, and a large number of other notable differences in the structure and function of mitochondria between normal and cancer cells have been discovered at the genetic, molecular, and biochemical levels. The purpose of this Special Issue is to provide an overview of the known differences in mitochondria structure and function between normal and cancer cells, and to highlight recent advances in our understanding of the role that mitochondria might play in the development, detection, and treatment of cancer. The submission of either primary research or review articles is encouraged.
Dr. Josephine S. Modica-Napolitano
Guest Editor
Manuscript Submission Information
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Keywords
- mitochondria
- cancer
- Warburg effect
- mitochondrial dysfunction in cancer
- mtDNA mutations
- mitochondrial bioenergetics
- tumor metabolism
- metabolic plasticity
- cancer detection
- mitochondria-targeted cancer treatment