The One Health paradigm claims that the health of humans is connected to the health of animals, plants, and the environment. Indeed, an estimated 60% of human pathogens originate in animals, about three-quarters of which are of wildlife origin. This holistic vision implies a coordinated, collaborative, multidisciplinary, and cross-sectoral approach to tackle threats that can originate at the environment–plant–animal–human interface while protecting biodiversity. Because the health of people, animals, plants, and the environment is interconnected, this integrated approach needs specialists in complementary sectors that work together to address environment-related human and animal health risks, as well as to prevent and control diseases shared between animals (including livestock, wildlife, and pets) and humans. Furthermore, the application of a One Health approach is pivotal for achieving the UN Sustainable Development Goals according to the 2030 Agenda for Sustainable Development. Relevant topics in the One Health model include human and animal health, plant health, antimicrobial resistance, food security, food safety, and no less important sustainable agriculture. Indeed, good agricultural practices are essential to manage plant diseases and produce enough food free from mycotoxins and pesticide residues to feed all people. In other words, the One Health vision is a unifying force to safeguard human and animal health, to reduce disease threats, and to ensure a safe food supply through effective and responsible management of natural resources.

Within this broad context, this Topical Collection welcomes original research and review articles focusing on biochemical and molecular aspects at the base of the One Health approach.

Prof. Dr. Marcello Iriti
Guest Editor

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• infectious diseases
• infection disease surveillance
• emerging diseases
• zoonoses
• environmental medicine
• plant health and diseases
• biodiversity
• food security and safety
• feed security and safety
• malnutrition
• mycotoxins and mycotoxicosis
• pesticides
• public health
• global climate change