Molecular Advances in Gestational Diabetes Mellitus

Dear Colleagues,

Gestational diabetes mellitus (GDM) is increasing in prevalence globally, and it is substantially related to an increased risk of type 2 diabetes (T2DM) after pregnancy in both pregnant women and their offspring. Little is known about how modifiable risk factors act on a mechanistic level to lower the longer-term risk of T2DM in women and their offspring.

In this Special Issue, entitled “Molecular Advances in Gestational Diabetes Mellitus”, we aim to present papers which deal with the newest research in the field of the molecular mechanisms that underpin the transgenerational impact of GDM. We welcome reviews and original research papers from fundamental and clinical research addressing how the maternal metabolome, placental signaling pathways, umbilical cord DNA methylation, and stem cell differentiation in GDM pregnancies compare to non-GDM pregnancies, as well as the impact of lifestyle, metformin, and insulin on treatment pathways.

Dr. Natasha Singh
Guest Editor

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• metabolome
• placental insulin signaling
• DNA methylation
• mitochondrial oxidation
• MTOR
• amino acids lipidomics
• proteomics
• gluconeogenesis
• GDM