Tumor-Immune Interactions

Dear Colleagues,

At present, there is no doubt that intervening in tumor immune interactions is among the most effective approaches for treating cancer. Key immune checkpoints, such as CTLA4/B7 and PD-1/PDL1, have been identified as targets, leading to immune system activation and tumor regression. The inherent complexity of the immune system is essential for its function, enabling it to combat a wide range of infections and abnormal cells. This versatility is made possible by numerous molecular interactions forming the foundation of immune functioning, involving various cell types and molecular pathways.

The challenge for the scientific community lies in unraveling the molecular interactions central to tumor-immune dynamics. This exploration will unveil new targets to augment the existing repertoire of immune checkpoints, providing additional avenues for effective cancer therapies.

Authors are encouraged to submit papers spanning basic research to preclinical studies on tumor-immune interactions, encompassing innovative therapeutic approaches, with a particular emphasis on molecular aspects. Additionally, we welcome papers reporting clinical studies with a well-defined experimental biomolecular foundation.

Dr. Peter J. K. Kuppen
Guest Editor

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• tumor-immune interactions
• molecular interactions
• tumor-immune dynamics
• immune checkpoints