Fate of Pancreatic Islets in Type 2 Diabetes—2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 29 May 2024 | Viewed by 140
Special Issue Editors
Interests: diabetes; endocrinology; beta cell viability; insulin signaling; mTORC1; exosome
Special Issues, Collections and Topics in MDPI journals
Interests: diabetes; insulin; islet; beta cell; cellular plasticity; dedifferentiation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the development of type 2 diabetes, the function and volume of pancreatic β-cells have been known as important factors. In particular, pancreatic β-cell mass is regulated by various factors. Recent studies have revealed that dedifferentiation is associated with the regulation of pancreatic β-cell mass in addition to proliferation and apoptosis. This Special Issue of IJMS is focused on the molecular mechanisms of pancreatic β-cell fate and aims to discuss the underlying mechanisms and downstream pathways involved in the pathogenesis of pancreatic β-cell failure. We welcome unique and creative basic research on the mechanisms of proliferation, apoptosis, transdifferentiation, neogenesis, and dedifferentiation of pancreatic β-cells. We look forward to your contributions.
Dr. Shunichiro Asahara
Dr. Katsuya Tanabe
Guest Editors
Manuscript Submission Information
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Keywords
- pancreatic β-cell
- dedifferentiation
- apoptosis
- proliferation
- neogenesis
