Advances in DNA-Metal Complex Interactions
A special issue of Inorganics (ISSN 2304-6740). This special issue belongs to the section "Bioinorganic Chemistry".
Deadline for manuscript submissions: closed (15 September 2022) | Viewed by 701
Special Issue Editor
Interests: metal binding; DNA; anticancer; amyloid protein; metal nanoparticles; antiparasitics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Since the breakthrough cementing our understanding of the cisplatin binding to DNA upon ligand exchange and its strong antiproliferative action, the study of DNA–metal complex interactions has accompanied the development of metal-based therapeutics for decades. The coordination and redox properties of metal ions along with the multifaceted role of ligands bestow metal complexes with a great versatility for the binding and cleavage of DNA, a biomolecule that remains a primary therapeutic target. Indeed, an increasing number of metal complexes have been reported as showing diverse binding modes and promising biological properties. Notwithstanding, recent advances in the recognition of non-canonical DNA structures, stimuli-responsive interactions, and sequence specificity modifications by metal complexes are propelling novel strategies for the effective transcription inhibition and regulation of this key biomolecule in cell proliferation.
This Special Issue aims to cover the most recent advances in all of these aspects of DNA–metal complex interactions by hosting a mix of original research articles and short critical reviews.
Dr. Ana B. Caballero
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Inorganics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- DNA interaction
- metal–nucleobase coordination
- supramolecular recognition
- metallonuclease
- photoactivated cleavage
- DNA modification
