Cardiac Ion Channels in Cardiac Health and Disease

Dear Colleagues,

JCDD is launching a Special Issue on "Cardiac Ion channels in Cardiac Health and Disease". Electrical activity in the heart is coordinated by the propagation of excitatory stimuli through cardiac tissue, which is mainly composed of cardiomyocytes. Action potential formation in the cardiomyoctes results from the gating of ion channels expressed at the plasma membrane (i.e., sarcolemma). Intracellular ion channels/transporters located at various organelles, including sarcoplasmic reticulum and mitochondria, also influence the ion channel gating properties at the sarcolemma. The importance of ion channels in maintaining normal action potential formation is reflected by the increased incidence of arrhythmias, both in inherited and in acquired cardiac diseases. The purpose of this Special Issue is to broadly summarize recent advances in the field of cardiac ion channel research. We welcome experts on this research field to share their original research, as well as methods and opinions, on this topic, and/or to submit solid review papers and perspectives to bring forward hypotheses that provide new avenues for bridging the gap between advances in basic science and the development of new therapies for cardiac arrhythmia.

Prof. Dr. Samuel C. Dudley
Dr. Jin O-Uchi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Cardiovascular Development and Disease is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• Arrhythmia
• Transporter
• Calcium
• Post-translational modifications
• Electrophysiology
• E-C Coupling