Skin Wound Healing and Regeneration in Vertebrates

Dear Colleagues,

The process of wound healing of the skin varies broadly among different species of vertebrates and also depends on the age of the injured animal. Scarring is a common result of wound healing in adult amniotes (reptiles, birds and mammals), while in anamniotes (fish and amphibians), the skin repairs well and with little or no scars. Some reptiles can also repair skin wound without scarring but this only occurs for relatively small wounds. The reason for this difference in aquatic versus terrestrial species is only partially known, but it largely derives from the inflammation and immune reaction that follows the wound, which is more intense in amniotes than in anamniotes, and from the type of immune cells that are activated during inflammation.

This Special Issue aims to delineate the variable healing capability among vertebrates. Original or review manuscripts are welcome, dealing with wound healing processes present in aquatic vertebrates, fish, and tetrapods that spend part of their life in water and part in humid or drier land conditions, including amphibians. Finally, manuscripts on the limited healing ability of the skin in reptiles, birds, and mammals are also welcomed for the Special Issue. Common and different processes of skin healing and regeneration in anamniotes and amniotes will be considered. The Special Issue is meant to summarize the present information on the different healing abilities of the wounded skin in aquatic versus terrestrial vertebrates.

Dr. Lorenzo Alibardi
Guest Editor

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• vertebrates
• skin and wound
• scarring and healing
• skin repair
• regeneration

• Development of the Skin in Vertebrates in Journal of Developmental Biology (11 articles)