Surface Modification of Magnetic Nanoparticles and Their Applications

A special issue of Magnetochemistry (ISSN 2312-7481). This special issue belongs to the section "Magnetic Nanospecies".

Deadline for manuscript submissions: closed (15 October 2023) | Viewed by 2803

Special Issue Editor

School of Physics and Astronomy, Faculty of Engineering and Physical Sciences, University of Southampton, Southampton SO171BJ, UK
Interests: magnetic nanostructures synthesis; surface modification; magnetic imaging; magnetic hyperthermia; drug delivery; biosensing; cancer diagnosis and therapy

Special Issue Information

Dear Colleagues,  

In recent decades, magnetic nanoparticles have shown significant potential in many applications because of their unique physical and chemical properties. Their outstanding magnetic properties, in conjunction with facile synthesis and surface modification methods, lead to broadly successful applications of these functional nanoparticles. For example, homogeneous catalysts are usually immobilized with magnetic nanoparticles because of their simple separation for reuse, while magnetic heterostructures exhibit higher efficiency in heterogeneous catalysis. Moreover, these nanoparticles are employed in the magnetical separation of various pollutants. Magnetic nanoparticles are also widely used as contrast agents for magnetic resonance imaging, while their capability to generate heat under external alternating magnetic filed causes them to kill cancer cells in magnetic hyperthermia. In addition, magnetic iron oxide nanoparticles are used as an immunoadjuvant in cancer immunotherapy.

In this special issue, we focus on the surface chemistry of magnetic nanoparticles in order to produce functional magnetic systems and their successful validation in different fields. In particular, i) the development of novel synthetic routes for the production of various magnetic nanostructures with a tunable size, shape, and composition, ii) different surface modification approaches such as ligand exchange, polymer coating, and silica coating for as-synthesized nanoparticles to obtain nanoparticles with better colloidal stability and tunable surface chemistry, iii) further exploitation of desired conjugation strategies for specific applications, iv) the effect of surface chemistry on magnetic properties followed by their efficiency in the applications, and v) the successful applications of designed magnetic nanosystems in diverse fields such as bioimaging, biosensing, drug delivery, therapy, catalysis, and water purification are covered.

Dr. Pradip Das
Guest Editor

Manuscript Submission Information

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Keywords

  • synthetic route
  • surface modification approach
  • magnetic properties
  • biosensing
  • bioimaging
  • drug delivery
  • therapy
  • catalysis
  • magnetic separation
  • water purification

Published Papers (1 paper)

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Research

16 pages, 4483 KiB  
Article
Synthesis and Characterization of Magnetic Molecularly Imprinted Polymer for the Monitoring of Amoxicillin in Real Samples Using the Chromatographic Method
by Rosario López, Sabir Khan, Sergio Espinoza Torres, Ademar Wong, Maria D. P. T. Sotomayor and Gino Picasso
Magnetochemistry 2023, 9(4), 92; https://doi.org/10.3390/magnetochemistry9040092 - 29 Mar 2023
Cited by 5 | Viewed by 1977
Abstract
Amoxicillin (AMX) is an antibiotic frequently used for the treatment of bacterial disorders and respiratory problems in both humans and animals. This work aims to synthesize a molecularly imprinted superparamagnetic polymer (SP-MIP) with a core-shell structure for the selective detection of AMX in [...] Read more.
Amoxicillin (AMX) is an antibiotic frequently used for the treatment of bacterial disorders and respiratory problems in both humans and animals. This work aims to synthesize a molecularly imprinted superparamagnetic polymer (SP-MIP) with a core-shell structure for the selective detection of AMX in real samples. Magnetite superparamagnetic nanoparticles (SNP) were prepared by the polyol method, coated with silica, and functionalized with silane groups. The polymerization process was executed using the free-radical precipitation method. Thermogravimetric analysis (TGA) was used to evaluate the thermal stability of the synthesized materials. The results obtained from N2 adsorption and desorption analyses showed that the surface area of SP-MIP (19.8 m2/g) was higher than that of the non-molecularly imprinted superparamagnetic polymer (SP-NIP—9.24 m2/g). The optimized adsorption analysis showed that both SP-MIP and SP-NIP followed SIP-type behavior, with adsorption constant KS 0.01176, 1/n 1.73. The selectivity tests showed that SP-MIP is highly selective for AMX in the presence of other molecules. Finally, for the recovery analysis, the application of SP-MIP for determining AMX in samples of tap water, river water, and drugs using HPLC yielded a mean recovery value of 94.3%. Full article
(This article belongs to the Special Issue Surface Modification of Magnetic Nanoparticles and Their Applications)
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