Bioactive Natural Products From the Deep-Sea-Sourced Microbes

Dear Colleagues

Deep-sea-sourced microbes, thriving in extreme environments characterized by high pressure, low temperatures, limited nutrients, and darkness, produce a diverse array of secondary metabolites with unique chemical structures and potent biological activities. In recent years, bioactive natural products derived from deep-sea-sourced microbes have garnered significant attention due to their novel structures and potential pharmaceutical applications.

Scientists have explored various deep-sea habitats, including cold seeps, hydrothermal vents, sediments, and deep-sea waters, to isolate and characterize microbes capable of producing bioactive compounds. These metabolites exhibit a wide range of biological activities, including antibacterial, antiviral, antitumor, and anti-inflammatory pharmacological activities, among others, making them promising candidates for drug discovery and development.

This Special Issue aims to highlight the discovery and bioactivities of natural products obtained from deep-sea-sourced microbes. Research papers and reviews focusing on topics such as the isolation, structural identification, biosynthesis, and action mechanisms of bioactive compounds discovered from deep-sea-sourced microbes are welcome for submission.

Prof. Dr. Bin-Gui Wang
Dr. Siwen Niu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• deep-sea-sourced fungus
• deep-sea-sourced actinomycetes
• deep-sea-sourced bacteria
• marine natural products
• bioactive natural products
• structure identification
• antibacterial activity
• antiviral activity
• anti-inflammatory activity
• cytotoxicity