Metabolomics Tools for Marine Natural Product Discovery

Dear Colleagues,

In recent years, the discovery process of Natural Products (NPs) has evolved to rely more on analytical chemistry due to its increased accuracy in detecting molecules, even at trace amount. Nowadays, comparative high resolution and sensitive metabolite profiling techniques are increasingly being used at every step of the NP discovery process. For this, either mass spectrometry or NMR analyses are combined or not with chemometrics. Marine Natural Product (MNP) researchers have been pioneers in the use of such approaches.

However, the big data often generated by such metabolomics approach require new developments to allow for a comprehensive and in-depth view of marine chemical diversity. Thus, the next frontier in MNP discovery relies on overcoming such data analysis challenges by proposing novel tools. In addition, new applications of currently employed techniques must emerge for the discovery of biologically and ecologically relevant marine molecules.

This Special Issue of Marine Drugs focusses on gathering articles dealing with:

• Novel metabolomics strategies (analytical and/or data mining approaches) that are able to deal with marine chemical diversity;
• Examples of the use of metabolomics and de novo dereplication strategies in MNP discovery context.

Dr. Samuel Bertrand
Prof. Dr. Olivier Grovel
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• Chemical profiling
• Data analysis
• Data fusion
• Dereplication
• Mass spectrometry
• Metabolomics
• NMR