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Bioactive Materials for Additive Manufacturing
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Bioactive Materials for Additive Manufacturing

A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".

Deadline for manuscript submissions: 20 October 2024 | Viewed by 2456

Special Issue Editor

Dr. Radosław Wichniarek

E-Mail Website
Guest Editor
Faculty of Mechanical Engineering, Poznan University of Technology, Piotrowo 3 STR, 61-138 Poznan, Poland
Interests: additive manufacturing; 3D printing; biomedical engineering; rapid prototyping; rapid manufacturing; mass customization; fused filament fabrication; virtual and augmented reality
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Additive manufacturing, commonly known as 3D printing, is revolutionizing the field of manufacturing and production. This technology has become ubiquitous in a wide range of industrial and consumer applications, from aerospace to automotive, healthcare to construction, and everything in between. In recent years, the use of AM has also been expanded to biomedical applications through the production of a class of materials that exhibit specific responses to biological systems, interact with living tissue, regenerate damaged organs and tissues, and improve overall health and well-being. As such, they are being studied extensively for use in various biomedical applications such as tissue engineering, drug delivery, and orthopedic implants. Through this Special Issue, we hope to inspire researchers and academics to explore the vast potential of bioactive materials for AM and contribute to the development of the field through their research.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Applying additive manufacturing to fabricate responsive biomaterials for drug delivery and therapeutic applications.
  • Enhancing the properties of polymeric materials with nanoparticles for safe use in drug delivery applications.
  • Biocompatible and mechanically robust materials for orthopedic implants.
  • Hybrid materials for advanced biomedical applications.
  • Bioactive materials in dental applications.

Dr. Radosław Wichniarek
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • additive manufacturing
  • 3D printing
  • bioactive materials
  • drug delivery
  • tissue engineering
  • medical materials
  • hydrogels, microgels and nanogels
  • biocompatibility
  • biopharmaceutical manufacturing
  • bioactive coatings

Published Papers (3 papers)

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Editorial

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2 pages, 180 KiB  
Editorial
Special Issue: Bioactive Materials for Additive Manufacturing
by Radosław Wichniarek
Materials 2023, 16(18), 6129; https://doi.org/10.3390/ma16186129 - 8 Sep 2023
Cited by 1 | Viewed by 558
Abstract
The Special Issue, entitled “Bioactive Materials for Additive Manufacturing”, aims to cover cutting-edge research regarding the production, characterization and application of bioactive materials that can be processed using additive manufacturing technology [...] Full article
(This article belongs to the Special Issue Bioactive Materials for Additive Manufacturing)

Research

Jump to: Editorial

22 pages, 10268 KiB  
Article
Investigation of the Structure-Forming Potential of Protein Components in the Reformulation of the Composition of Edible Films
by Monika Janowicz, Sabina Galus, Karolina Szulc, Agnieszka Ciurzyńska and Małgorzata Nowacka
Materials 2024, 17(4), 937; https://doi.org/10.3390/ma17040937 - 17 Feb 2024
Viewed by 813
Abstract
To optimize the functional properties of edible films or coatings, mixtures of several ingredients are used, including food processing by-products. In this way, pectin from fruit pomace, whey proteins from whey as a by-product of rennet cheese production, and gelatin from by-products of [...] Read more.
To optimize the functional properties of edible films or coatings, mixtures of several ingredients are used, including food processing by-products. In this way, pectin from fruit pomace, whey proteins from whey as a by-product of rennet cheese production, and gelatin from by-products of the processing of slaughtered animals can be obtained. The aim and scope of the investigation were to verify the hypothesis of the research, which assumes that the addition of beef broth to edible gelatin films will affect the gelation processes of the tested film-forming solutions and will allow for the modification of the edible properties of the films obtained based on these solutions. Measurements were carried out to determine the visual parameters, mechanical strengths, surface and cross-sectional structures, FTIR spectra, thermal degradation rates, and hydrophilicities of the prepared gelatin films. The water content, water vapor permeability, and course of water vapor sorption isotherms of the films were also examined, as well as the course of the gelation process for film-forming solutions. The addition of broth to film-forming solutions was found to increase their opacity and color saturation, especially for the ones that were yellow. The films with the addition of broth were more uneven on the surface and more resistant to stretching, and in the case of the selected types of gelatins, they also formed a more stable gel. The broth increased the hydrophilicity and permeability of the water vapor and reduced the water content of the films. The addition of broth enables the practical use of edible films, but it is necessary to modify some features. Full article
(This article belongs to the Special Issue Bioactive Materials for Additive Manufacturing)
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11 pages, 2066 KiB  
Article
Photopolymer-Based Composite with Substance Release Capability Manufactured Additively with DLP Method
by Dorota Tomczak, Sławomir Borysiak, Wiesław Kuczko, Ariadna B. Nowicka, Tomasz Osmałek, Beata Strzemiecka and Radosław Wichniarek
Materials 2024, 17(2), 322; https://doi.org/10.3390/ma17020322 - 9 Jan 2024
Viewed by 733
Abstract
In this study, caffeine-loaded photoresin composites with homogeneous structures, suitable for additive manufacturing of transdermal microneedle systems, were obtained. The properties of the composites with varying caffeine concentrations (0.1–0.4% w/w) were investigated for carbon–carbon double bond conversion using Fourier Transform [...] Read more.
In this study, caffeine-loaded photoresin composites with homogeneous structures, suitable for additive manufacturing of transdermal microneedle systems, were obtained. The properties of the composites with varying caffeine concentrations (0.1–0.4% w/w) were investigated for carbon–carbon double bond conversion using Fourier Transform Infrared Spectroscopy, surface wettability and mechanical properties using a static tensile test and nanoindentation, and caffeine release in ethanol using UV-Vis. The caffeine concentration did not affect the final degree of double bond conversion, which was confirmed in tensile tests, where the strength and Young’s modulus of caffeine-loaded samples had comparable values to control ones. Samples with 0.1 and 0.2% caffeine content showed an increase in nanohardness and reduced elastic modulus of 50 MPa and 1.5 MPa, respectively. The good wettability of the samples with water and the increase in surface energy is a favorable aspect for the dedicated application of the obtained composite materials. The amount of caffeine released into the ethanol solution at 1, 3 and 7 days reached a maximum value of 81%, was higher for the lower concentration of caffeine in the sample and increased over time. The conducted research may enhance the potential application of composite materials obtained through the digital light processing method in additive manufacturing. Full article
(This article belongs to the Special Issue Bioactive Materials for Additive Manufacturing)
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