Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.2
3.4
Journals
Materials
Special Issues
Biocompatible Metals for Skeletal Fixation and Joint Replacement Devices
materials-logo
Submit to Materials Review for Materials Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Biocompatible Metals for Skeletal Fixation and Joint Replacement Devices

A special issue of Materials (ISSN 1996-1944).

Deadline for manuscript submissions: closed (30 November 2018) | Viewed by 10297

Special Issue Editors

Dr. David Dean

E-Mail Website
Guest Editor
Department of Plastic Surgery, Ohio State University, Columbus, OH 43210, USA
Interests: skeletal reconstructive surgery; point-of-care manufacturing; biomanufacturing; biofabrication; virtual surgical planning
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Mohammad Elahinia

E-Mail Website
Guest Editor
Dynamic and Smart Systems Laboratory, Department of Mechanical Industrial and Manufacturing Engineering, The University of Toledo, Toledo, OH 43606, USA
Interests: additive manufacturing; 3D printing; shape memory alloys; materials engineering; finite element analysis; control systems engineering; product design and development; electrical engineering; design engineering; product development; manufacturing process mechanics; mechanical processes; machining; experimental analysis of behavior; design optimization; MR fluids; mechanical vibrations; medical devices; computer-aided engineering
Special Issues, Collections and Topics in MDPI journals
Dr. Jason Walker

E-Mail Website
Guest Editor
Center for Innovation in Additive Manufacturing, Department of Mechanical & Industrial Engineering, Youngstown State University, Youngstown, OH 44555, USA
Interests: additive manufacturing; 3D printing; aerospace engineering; shape memory alloys; tissue engineering; medical device design; materials engineering; machining; design optimization; computer-aided engineering; finite element analysis

Special Issue Information

Dear Colleagues,

Surgical Grade 5 Titanium (Ti-6Al-4V) is the standard of care material for metallic implants, used in hundreds of thousands of clinical implants annually. In addition to titanium, many other metals are gaining attention for their advantageous mechanical or resorbable properties. Both stress shielding of replaced or fixated bone, or stress concentrations in the device itself, are thought to be a common cause of short or long-term device failure. Less stiff metals such as nitinol (NiTi) are thought to be good candidates for fixation, joint replacement, and other devices because of their lower stiffness as well as their superelastic properties. Other metals, including magnesium (Mg) alloys that can resorb in a controlled and safe fashion, are also being studied as a means of providing skeletal fixation and to avoid long term stress shielding and stress concentrations. The metallurgy needed to form these alloys into biocompatible materials that can be fabricated (molten, solid ingots, or powders for 3D printing), especially if patient-specific designs are desired, present special challenges. This Special Issue of Materials, “Biocompatible Metals for Skeletal Fixation and Joint Replacement Devices”, promises to be a resource to the biomedical and biomaterial communities for some time to come.

Assoc. Prof. Dr. David Dean
Prof. Dr. Mohammad Elahinia
Dr. Jason Walker
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Stress shielding
  • Stress concentration
  • Skeletal fixation
  • Joint replacement
  • Ti-6Al-4V (Surgical Grade 5 Titanium)
  • NiTi
  • Beta titanium alloys
  • Magnesium
  • Shape memory
  • Superelasticity

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

11 pages, 26925 KiB  
Article
Surface Modification of Ti-35Nb-10Ta-1.5Fe by the Double Acid-Etching Process
by Joan Lario, Angélica Amigó, Francisco Segovia and Vicente Amigó
Materials 2018, 11(4), 494; https://doi.org/10.3390/ma11040494 - 26 Mar 2018
Cited by 5 | Viewed by 3775
Abstract
Surface topography and composition influence the osteoblastic proliferation and osseointegration rates, which favor the biomechanical stability of bone anchoring and implants. In recent years, beta titanium alloys have been developed, and are composed of biocompatible elements, have low elastic modulus, high corrosion resistance, [...] Read more.
Surface topography and composition influence the osteoblastic proliferation and osseointegration rates, which favor the biomechanical stability of bone anchoring and implants. In recent years, beta titanium alloys have been developed, and are composed of biocompatible elements, have low elastic modulus, high corrosion resistance, and mechanical properties to improve the long performance behavior of biomaterials. In the present research, the influence of the acid-etching process was studied in Ti6Al4V ELI and Ti35Nb10Ta1.5Fe. Samples were etched in a two-step acid treatment. Surface roughness parameters were quantified under a confocal microscope, topography was studied by scanning electron microscopy, and surface composition was analyzed with energy dispersive X-ray spectroscopy. The results revealed that the two-step acid treatment changes the topography of the β alloy, increases the surface area, and changes the chemical composition of the surface. Two differentiated regions were identified in the Ti35Nb10Ta1.5Fe alloy after the acid-etching process: The α + β region with higher values of mean roughness due to the lower chemical resistance of this region; and the β region with lower values of roughness parameters. Full article
(This article belongs to the Special Issue Biocompatible Metals for Skeletal Fixation and Joint Replacement Devices)
►▼ Show Figures

Graphical abstract

7077 KiB  
Article
Evaluation of the Healing Potential of Demineralized Dentin Matrix Fixed with Recombinant Human Bone Morphogenetic Protein-2 in Bone Grafts
by Sang-Yun Kim, Young-Kyun Kim, Yeoung-Hyun Park, Joo-Cheol Park, Jeong-Kui Ku, In-Woong Um and Ji-Yun Kim
Materials 2017, 10(9), 1049; https://doi.org/10.3390/ma10091049 - 07 Sep 2017
Cited by 42 | Viewed by 5766
Abstract
We aimed to evaluate the efficacy of demineralized dentin matrix (DDM) fixed with recombinant human bone morphogenetic protein-2 (rhBMP-2) through an experimental and a clinical study. Unilateral upper second and third premolars of eight beagles were extracted. A mucoperiosteal flap was elevated around [...] Read more.
We aimed to evaluate the efficacy of demineralized dentin matrix (DDM) fixed with recombinant human bone morphogenetic protein-2 (rhBMP-2) through an experimental and a clinical study. Unilateral upper second and third premolars of eight beagles were extracted. A mucoperiosteal flap was elevated around the extraction socket, and a bone defect was made using a surgical drill. Each DDM was fixed with rhBMP-2, and autogenous bone was grafted at the bone defect area with a collagenous membrane. The beagles were euthanized at two, four, eight, and 12 weeks after receiving the bone graft. Block specimens involving grafted bone and surrounding natural bone were extracted. A total of 23 patients who received bone grafts using human DDM fixed with rhBMP-2 (AutoBT BMP) with implant placements (36 implants; maxilla: 14, mandible: 22) were selected. The implant stability, marginal bone loss, and clinical outcome were evaluated. Three trephine cores were harvested fourmonths after bone grafting, and histologic examination was performed. In the histological evaluation performed four weeks after the bone graft, autogenous bone showed 52% new bone formation and DDM fixed with rhBMP-2 showed 33% new bone formation. Twelve weeks after the bone graft, autogenous bone showed 75% new bone formation and DDM fixed with rhBMP-2 showed 48% new bone formation. In the clinical study, favorable osseointegration was obtained in 35 out of 36 implant sites (one case of osseointegration failure). In all cases, severe complications were not observed. Histomorphometrically, new bone formation was observed in 14.98% of the cases. The residual DDM particles were 6.22%. AutoBT BMP provides good osteoinductive and osteoconductive potential and clinical efficacy. Full article
(This article belongs to the Special Issue Biocompatible Metals for Skeletal Fixation and Joint Replacement Devices)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop