Erectile Dysfunction in Men with Chronic Diseases: The Treatment before Treatment, Pathophysiology and Novel Therapeutic Approaches
A special issue of Medicines (ISSN 2305-6320).
Deadline for manuscript submissions: closed (30 September 2020) | Viewed by 16018
Special Issue Editor
2. 2nd Urological Department, Attikon Hospital, Medical School of Athens, National and Kapodistrian University of Athens, 1 Rimini st, 124 62 Athens, Greece
3. Androclinic, Andrological Institute, 4 Valaoritou str, 106 71 Athens, Greece
Interests: andrology; general urology (BPH, stones, urological cancers)
Special Issue Information
Dear colleagues,
Erectile dysfunction (ED) is a problem that affects millions of people worldwide. The causes can be either organic or psychogenic, with the first predominate being increasing age. Although the final step is erectile tissue dysfunction expressed as decreased relaxation, different underlying mechanisms exist (endothelial, connective tissue, or neurological dysfunction). The current treatments mainly focus on improving endothelial-induced vasodilation and, therefore, are a symptomatic rather than causative treatment. Since many chronic conditions can be the cause of ED with known or unknown pathophysiological mechanisms, treatment of the underlying condition can prevent or improve erectile dysfunction. Diabetes mellitus, metabolic syndrome, hormonal and vitamin dysfunction (like hypogonadism, hyperthyroidism, vitamin D deficiency), renal deficiency, neurologic diseases, inflammatory bowel disease, chronic fatigue syndrome, sleep disorders, chronic liver diseases, chronic periodontitis, autoimmune diseases, and even commonly used drug-induced side effects like antipsychotic and antidepressant medications are some of the chronic conditions that if treated can improve erectile function. Novel treatments that are considered curative, like low-intensity shock waves, PRP, and stem cells are also emerging as new players in ED.
The current issue is focusing on the pathophysiological mechanisms that link chronic diseases with ED and investigating possible novel treatments in the field of erectile dysfunction.
Dr. Vassilis Protogerou
Guest Editor
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Keywords
- erectile dysfunction
- chronic diseases
- diabetes mellitus
- metabolic syndrome
- autoimmune diseases
- inflammatory bowel disease
- neurologic diseases
- chronic fatigue syndrome
- antipsychotic and antidepressant medications
- novel treatments
