Medical Sciences

Special Issue Editor

Dr. Rüdiger Klapdor

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Guest Editor

Department of Gynecology and Obstetrics and Institute of Experimental Hematology, Hannover Medical School, 30625 Hannover, Germany
Interests: gynecologic oncology; surgical oncology; ovarian cancer; cervical cancer; endometrial cancer; vulvar cancer; immunology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The field of gynecologic oncology has experienced some impressive developments over the last few years. The already established surgical treatment of ovarian or cervical cancer has been questioned and partly changed. The inferiority of laparoscopic radical hysterectomy in the LACC study led to one of the most controversial discussions in recent years. Radical lymph node dissection was not shown to improve survival in advanced ovarian cancer. Sentinel lymph node dissection became standard in vulvar cancer. Therefore, we ask ourselves: Which of our therapeutical strategies are really based on reliable evidence? How can we improve the implementation of novel surgical techniques without delaying invention? Do these large randomized controlled trials really answer the intended questions? What role will surgical oncology play in the future? We urgently need larger randomized controlled trials. However, we also need to analyze real-world data and retrospective cohorts to generate new hypotheses which can then be specifically addressed in large prospective studies. The goal of this Special Issue is to present new hypotheses and new results regarding surgical gynecological oncology.

Dr. Rüdiger Klapdor
Guest Editor

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Keywords

gynecologic oncology
surgical oncology
ovarian cancer
cervical cancer
endometrial cancer
vulvar cancer
radical hysterectomy
lymph node dissection
sentinel lymph node

Published Papers (2 papers)

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Review

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18 pages, 1445 KiB

Open AccessReview

Novel Vaccine Strategies and Factors to Consider in Addressing Health Disparities of HPV Infection and Cervical Cancer Development among Native American Women

by Crystal G. Morales, Nicole R. Jimenez, Melissa M. Herbst-Kralovetz and Naomi R. Lee

Med. Sci. 2022, 10(3), 52; https://doi.org/10.3390/medsci10030052 - 13 Sep 2022

Viewed by 3852

Abstract

Cervical cancer is the 4th most common type of cancer in women world-wide. Many factors play a role in cervical cancer development/progression that include genetics, social behaviors, social determinants of health, and even the microbiome. The prevalence of HPV infections and cervical cancer is high and often understudied among Native American communities. While effective HPV vaccines exist, less than 60% of 13- to 17-year-olds in the general population are up to date on their HPV vaccination as of 2020. Vaccination rates are higher among Native American adolescents, approximately 85% for females and 60% for males in the same age group. Unfortunately, the burden of cervical cancer remains high in many Native American populations. In this paper, we will discuss HPV infection, vaccination and the cervicovaginal microbiome with a Native American perspective. We will also provide insight into new strategies for developing novel methods and therapeutics to prevent HPV infections and limit HPV persistence and progression to cervical cancer in all populations. Full article

(This article belongs to the Special Issue Gynecologic Oncology – Old Controversies and New Strategies)

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Other

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8 pages, 1033 KiB

Open AccessBrief Report

SOCIUS Mentoring—A Novel Course to Encourage Students for a Career as Surgical Oncologists

by Rüdiger Klapdor, Moritz Kleine, Tobias Schilling, Stephan Huusmann, Anja Philippeit, Jill Philippeit, Kai Timrott, Marcus Kruppa, Peter Hillemanns and Florian Imkamp

Med. Sci. 2022, 10(3), 35; https://doi.org/10.3390/medsci10030035 - 24 Jun 2022

Cited by 2 | Viewed by 1835

Abstract

Surgical disciplines are affected by an increasing shortage of young doctors. Studies show that formerly interested students decide against a career in surgical disciplines at the end of their studies or during practical year. Measures to counteract this development are urgently needed. As a joint project between gynecology, urology, and general surgery, SOCIUS mentoring was designed to prepare and encourage students for a career in surgical oncology. The structured curriculum of SOCIUS mentoring contains six modules, including surgical skills, soft skills, mentoring, theory, clinical visitation, and congress participation and runs over one year. Effects on confidence towards physician skills and plans for a future career were evaluated with questionnaires. After participation, students reported increased confidence in surgical and soft skills. In addition, participants noted that they have specified their career goals and gained more confidence in surgery, as well as seeing more development potential for a career in surgery. We describe the implementation of a novel extracurricular program for motivated students that combines individual mentoring with surgical and soft skills training. Due to its modular structure, this concept can easily be transferred to other disciplines. SOCIUS mentoring, with its combination of mentoring and skills training, is a promising measure to prepare and motivate students for their surgical career and thus counteract the shortage of young talent. Full article

(This article belongs to the Special Issue Gynecologic Oncology – Old Controversies and New Strategies)

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