Metabolites: From Physiology to Pathology

Dear Colleagues,

It is a pleasure for us, to invite you to submit a review or a research article for publication in the Special Issue entitled “Metabolites: From Physiology to Pathology” for the journal Metabolites (MDPI).

Metabolite activity is a fascinating aspect of cellular metabolism because, through interaction, metabolites serve as direct modulators of biological processes and phenotypes. These findings have already shown the significant impact of metabolites on biological systems. However, more recently, with the advent and evolution of metabolomics technologies, the discovery of active metabolites with the capability to change cell physiology has grown rapidly. These studies highlight the intrinsic biological activity of metabolites and provide new import to the value of metabolomics, as a way to identify metabolites that act as drivers of biological processes and, thus, better understand their physiological role.

This Special Issue will include studies on the role of metabolites, not only as a "simple molecule involved in a physiological reaction" but as a predictive disease biomarker that could be used as a prognostic target in several disorders, metabolic and not. Research articles collecting data from both in vitro and in vivo investigations are welcome. In addition, review articles reporting on metabolites currently used as therapeutic targets or biomarkers would complete the topic.

Dr. Marika Cordaro
Ms. Rosalba Siracusa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.