The New Advance on Disinfectant of Virus and Microorganisms, 2nd Edition

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbial Biotechnology".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 876

Special Issue Editor


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Guest Editor
Laboratory of Environmental Science for Sustainable Development, Department of Veterynary Medical Science, Research Center for Food Safety, University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan
Interests: virology; immunology; prions
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Special Issue Information

Dear Colleagues,

This Special Issue is a continuation of our 2022 Special Issue "The New Advance on Disinfectant of Virus and Microorganisms".

Nanomaterials have the ability to prevent viral contamination by air and contact with contaminated surfaces and have the ability to sterilize protective equipment especially in hospital settings. Creating self-disinfeting surfaces is another strategy to prevent the spread of COVID-19.

Besides, non-thermal plasam application is a novel way in medical treatments. Development of coagulation methods using non-thermal plasma is critical for surgical application. Aragon plasma coagulation-assisted tonsillectomy reduced the oprtation time.  Reactive Oxygen Species are engages in the wound healing process during this oparation. More use of photocatalysis and UV-C is expected for the protective equipment of hospital settings besides mechanical ventilation. There are several products made of nanocomposites that have antimicrobial activities and used in the disinfection of surfaces. CAC-717 is a new disinfectant consisting of calcium bicarbonate mesoscopic crystals that are a compound containing mesostructured nanoparticles and are involved in inactivating enveloping and non-enveloping viruses. Graphene in face masks can also sterilize SARS-CoV-2 and allow them to be reused. This coating is also suitable for use on surface in public places. In Kampo medicine there are so many materials working for antiviral effects for SARS-CoV-2.

The unpredictable and unknown nature of COVID-19 and the similarity of the specific properties this disease and the physicochemical properties of nanosystems will lead to the discussion of solutions based on new technologies. 

Prof. Dr. Takashi Onodera
Guest Editor

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Keywords

  • Calcium bicarbonates
  • disinfection
  • Graphene
  • heated scallop-shell powder
  • photocatalysis
  • Kampo medicine
  • SARS-CoV-2

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Published Papers (1 paper)

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Research

12 pages, 2212 KiB  
Article
Decontamination of Fused-Silica Surfaces by UVC Irradiation as Potential Application on Touchscreens
by Ben Sicks, Oksana Gurow, Florian Sommerfeld and Martin Hessling
Microorganisms 2024, 12(10), 2099; https://doi.org/10.3390/microorganisms12102099 - 21 Oct 2024
Viewed by 547
Abstract
The contamination of surfaces by antibiotic-resistant pathogens presents an escalating challenge, especially on touchscreens in public settings such as hospitals, airports, and means of transport. Traditional chemical cleaning agents are often ineffective and leave behind harmful residues. Thus, the application of optical radiation [...] Read more.
The contamination of surfaces by antibiotic-resistant pathogens presents an escalating challenge, especially on touchscreens in public settings such as hospitals, airports, and means of transport. Traditional chemical cleaning agents are often ineffective and leave behind harmful residues. Thus, the application of optical radiation is gaining relevance as a rapid, effective, and environmentally friendly disinfection method. This study examines the contamination of publicly accessible touchscreens and the efficacy of an irradiation approach for the radiation disinfection of microorganisms on quartz surfaces with UVC LEDs. In this setup, the LED radiation is laterally coupled into a quartz plate that serves as cover glass of a simplified touchscreen model. The process allows for the irradiation of microorganisms on the surface, without the user being exposed to hazardous radiation. To assess the efficacy of the disinfection process, a range of bacteria, mostly ESKAPE surrogates, such as Staphylococcus carnosus, Acinetobacter kookii, Escherichia coli, Enterococcus mundtii, and additionally Micrococcus luteus, were spread over a quartz plate with a homebuilt nebulization system. After operating the side-mounted LEDs for 30 s, a reduction in all bacteria except M. luteus by more than three orders of magnitude was observed. In the case of M. luteus, a significant reduction was achieved after 60 s (p < 0.05). This result demonstrates the potential of side-mounted UVC LEDs for rapid disinfection of touchscreens between two users and thus for reducing the spread of pathogens without irradiating humans. Full article
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