Specialized Metabolites from Microorganisms
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbial Biotechnology".
Deadline for manuscript submissions: 30 November 2024 | Viewed by 21065
Special Issue Editor
Interests: sustainable textile; microbial biotechnology; microbial production of pigments and colorants; fermentation; bioprocess engineering and fermentation technology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Specialized metabolites, formerly (or usually) called secondary metabolites, toxins, secondary products, or natural products, are organic compounds produced by any lifeform, e.g. bacteria, fungi, animals, or plants, which are not directly involved in the normal growth, development, or reproduction of the organism. This Special Issue will only focus on microbial specialized metabolites, fully in line with Microorganisms ISSN 2076-2607 aims and scope (over 7,700 articles published since 1996, on October 17, 2022). Please have a look there: https://www.mdpi.com/search?q=&journal=microorganisms&sort=pubdate&page_count=50. Bacterial production of secondary metabolites starts in the stationary phase as a consequence of lack of nutrients or in response to environmental stress. Secondary metabolite synthesis in bacteria is often described as not essential for their growth, however, they allow them to better interact with their ecological niche. The main synthetic pathways of secondary metabolite production in bacteria are b-lactam, oligosaccharide, shikimate, polyketide and non-ribosomal pathways. Aspects about microbial specialized metabolites under consideration for publication in this Special Issue are listed below (non-exhaustive list, please contact the Guest Editor for any additional information):
- Specialized metabolites from bacteria, yeasts, fungi
- Analytical techniques for full chemical description of microbial specialized metabolites
- Transfer of plant specialized metabolites to microbial platforms
- Bioprospecting for new microbial specialized metabolites
- Subcellular localization of microbial specialized metabolites
- Machine learning discovery of missing links in microbial specialized metabolites biosynthesis
- Specialized metabolites of endophytes
- Cryptic specialized metabolites and how to reveal and express the genes coding for
- Mining biosynthetic gene clusters for new microbial specialized metabolites
- Mechanism-based approach to new antibiotic producers screening
- Engineering powerful green cell factories for robust microbial specialized metabolites production
- Specialized metabolite biosynthetic diversity encoded in microbial genomes
- Optimization of microbial specialized metabolites production in fermenters (fermenter design, pO2, pH, nutrients, agitation speed…); idem in Erlenmeyer flasks, microplates, photobioreactors, etc
- Excretion or in situ cell storage of microbial specialized metabolites
- Bottleneck removal of microbial specialized metabolites biosynthetic pathways
- CRISPR-Cas9 based genetic engineering of microbial specialized metabolites biosynthetic pathways
- Multiomics that reveal the effect(s) of microbial specialized metabolites
- Bioactivity of microbial specialized metabolites
- Role and genetic basis of specialized secondary metabolites in microbial ecophysiology
- Evolutionary genome mining for the discovery and engineering of specialized secondary metabolites
- Specialized microbial metabolite-mediated predation defense
- Strain improvement and strain maintenance revisited for production of specialized secondary metabolites
- Specialized secondary metabolites as big players in the pharma, feed or food business
- New microbial isolates as source of undiscovered specialized metabolites
Prof. Dr. Laurent Dufossé
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- specialized
- specialised
- secondary
- metabolite
- bacteria
- yeast
- fungus
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Planned Papers
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Pharmacological Potential, Anti-tumor, Antimicrobial and AChEI Evaluation of Marine-Derived Bacillus velezensis AG6 Exopolysaccharide: In-Vitro Studies
Author: Ghareeb
Highlights: This research elucidates the pharmacological potential of a secondary metabolite from marine Bacillus velezensis