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Synthesis, Characterization, and Biological Evaluation of Alkaloids

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 58

Special Issue Editor


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Guest Editor
Department of Resources Science of Traditional Chinese Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211198, China
Interests: utilization of chinese medicine resources; biosynthesis and synthetic biology of important natural products from plants; structural biology and catalytic mechanism of biosynthesis enzymes

Special Issue Information

Dear Colleagues,

Alkaloids are low-molecular-weight, nitrogen-containing compounds that are found in approximately 20% of plant species. They play a crucial role in medicine due to their significant biological activities. Recent advancements in genomics, transcriptomics, proteomics, metabolomics, and phenomics have enabled scientists to utilize modern technologies in the fields of synthesis, characterization, and biological evaluation of alkaloids, particularly focusing on biosynthesis and synthetic biology of key alkaloids like Vinblastine, Colchicine, Morphine, Codeine, and Scopolamine.

This research topic is dedicated to publishing original research articles and review articles that explore the application of omics approaches in studying the biosynthesis of important alkaloids derived from plants. Additionally, we welcome submissions on the structural biology and catalytic mechanisms of biosynthesis enzymes involved in alkaloid production. Contributions that involve the effective identification of molecules with novel structural features, isolation and characterization of trace amounts of natural products, derivatization of natural product analogs to investigate structure–activity relationships, and industrial total synthesis of complex active natural products through synthetic biology are encouraged.

Furthermore, research studies focusing on the application of omics technologies in the development and utilization of Chinese medicine resources are highly valued and welcome in this Special Issue. We look forward to receiving your innovative research contributions that shed light on the synthesis, characterization, and biological evaluation of alkaloids using cutting-edge omics technologies.

Dr. Yucheng Zhao
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biological evaluation
  • alkaloids
  • biosynthesis
  • synthetic biology
  • catalytic mechanism
  • biosynthesis enzymes

Published Papers

This special issue is now open for submission.
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